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c-Jun-NH2-kinase-1 inhibition leads to antitumor activity in ovarian cancer.
Vivas-Mejia P, Benito JM, Fernandez A, Han HD, Mangala L, Rodriguez-Aguayo C, Chavez-Reyes A, Lin YG, Carey MS, Nick AM, Stone RL, Kim HS, Claret FX, Bornmann W, Hennessy BT, Sanguino A, Peng Z, Sood AK, Lopez-Berestein G. Vivas-Mejia P, et al. Clin Cancer Res. 2010 Jan 1;16(1):184-94. doi: 10.1158/1078-0432.CCR-09-1180. Epub 2009 Dec 22. Clin Cancer Res. 2010. PMID: 20028751 Free PMC article.
Bcl-2 inhibits p53 nuclear import following DNA damage.
Beham A, Marin MC, Fernandez A, Herrmann J, Brisbay S, Tari AM, Lopez-Berestein G, Lozano G, Sarkiss M, McDonnell TJ. Beham A, et al. Oncogene. 1997 Dec 4;15(23):2767-72. doi: 10.1038/sj.onc.1201464. Oncogene. 1997. PMID: 9419967
Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial.
Hortobagyi GN, Ueno NT, Xia W, Zhang S, Wolf JK, Putnam JB, Weiden PL, Willey JS, Carey M, Branham DL, Payne JY, Tucker SD, Bartholomeusz C, Kilbourn RG, De Jager RL, Sneige N, Katz RL, Anklesaria P, Ibrahim NK, Murray JL, Theriault RL, Valero V, Gershenson DM, Bevers MW, Huang L, Lopez-Berestein G, Hung MC. Hortobagyi GN, et al. J Clin Oncol. 2001 Jul 15;19(14):3422-33. doi: 10.1200/JCO.2001.19.14.3422. J Clin Oncol. 2001. PMID: 11454891 Clinical Trial.
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma.
Thaker PH, Han LY, Kamat AA, Arevalo JM, Takahashi R, Lu C, Jennings NB, Armaiz-Pena G, Bankson JA, Ravoori M, Merritt WM, Lin YG, Mangala LS, Kim TJ, Coleman RL, Landen CN, Li Y, Felix E, Sanguino AM, Newman RA, Lloyd M, Gershenson DM, Kundra V, Lopez-Berestein G, Lutgendorf SK, Cole SW, Sood AK. Thaker PH, et al. Nat Med. 2006 Aug;12(8):939-44. doi: 10.1038/nm1447. Epub 2006 Jul 23. Nat Med. 2006. PMID: 16862152
Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.
Halder J, Kamat AA, Landen CN Jr, Han LY, Lutgendorf SK, Lin YG, Merritt WM, Jennings NB, Chavez-Reyes A, Coleman RL, Gershenson DM, Schmandt R, Cole SW, Lopez-Berestein G, Sood AK. Halder J, et al. Clin Cancer Res. 2006 Aug 15;12(16):4916-24. doi: 10.1158/1078-0432.CCR-06-0021. Clin Cancer Res. 2006. PMID: 16914580 Free PMC article.
Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer.
Landen CN, Merritt WM, Mangala LS, Sanguino AM, Bucana C, Lu C, Lin YG, Han LY, Kamat AA, Schmandt R, Coleman RL, Gershenson DM, Lopez-Berestein G, Sood AK. Landen CN, et al. Cancer Biol Ther. 2006 Dec;5(12):1708-13. doi: 10.4161/cbt.5.12.3468. Epub 2006 Dec 30. Cancer Biol Ther. 2006. PMID: 17106249
426 results