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KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC. Lee DF, et al. Among authors: kuo hp. Mol Cell. 2009 Oct 9;36(1):131-40. doi: 10.1016/j.molcel.2009.07.025. Mol Cell. 2009. PMID: 19818716 Free PMC article.
IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression.
Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, Dhar D, Karin M, Chen CH, Hung MC. Liu M, et al. Among authors: kuo hp. Mol Cell. 2012 Jan 27;45(2):171-84. doi: 10.1016/j.molcel.2011.11.018. Epub 2011 Dec 22. Mol Cell. 2012. PMID: 22196886 Free PMC article.
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. Yang JY, et al. Among authors: kuo hp. Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Nat Cell Biol. 2008. PMID: 18204439 Free PMC article.
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer.
Ding Q, Huo L, Yang JY, Xia W, Wei Y, Liao Y, Chang CJ, Yang Y, Lai CC, Lee DF, Yen CJ, Chen YJ, Hsu JM, Kuo HP, Lin CY, Tsai FJ, Li LY, Tsai CH, Hung MC. Ding Q, et al. Among authors: kuo hp. Cancer Res. 2008 Aug 1;68(15):6109-17. doi: 10.1158/0008-5472.CAN-08-0579. Cancer Res. 2008. PMID: 18676833 Free PMC article.
286 results