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27-hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7alpha,27-dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of ldl cholesterol can underlie a defective feedback control in malignant cells.
Axelson M, Larsson O. Axelson M, et al. Among authors: larsson o. J Biol Chem. 1996 May 31;271(22):12724-36. doi: 10.1074/jbc.271.22.12724. J Biol Chem. 1996. PMID: 8662693 Free article.
Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth.
Carlberg M, Dricu A, Blegen H, Wang M, Hjertman M, Zickert P, Höög A, Larsson O. Carlberg M, et al. Among authors: larsson o. J Biol Chem. 1996 Jul 19;271(29):17453-62. doi: 10.1074/jbc.271.29.17453. J Biol Chem. 1996. PMID: 8663239 Free article.
Inhibition of N-linked glycosylation using tunicamycin causes cell death in malignant cells: role of down-regulation of the insulin-like growth factor 1 receptor in induction of apoptosis.
Dricu A, Carlberg M, Wang M, Larsson O. Dricu A, et al. Among authors: larsson o. Cancer Res. 1997 Feb 1;57(3):543-8. Cancer Res. 1997. PMID: 9012488
Recent studies have shown that inhibition of N-linked glycosylation using tunicamycin (TM) induces cell death in cultured cells (O. Larsson et al., J. Cell Sci., 106: 299-307, 1993; J. Y. Chang and V. ...
Recent studies have shown that inhibition of N-linked glycosylation using tunicamycin (TM) induces cell death in cultured cells (O. …
540 results