Broughton SJ - Search Results

1

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition.

Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L. Broughton SJ, et al. Aging Cell. 2010 Jun;9(3):336-46. doi: 10.1111/j.1474-9726.2010.00558.x. Epub 2010 Feb 12. Aging Cell. 2010. PMID: 20156206 Free PMC article.

2

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs.

Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Broughton S, et al. PLoS One. 2008;3(11):e3721. doi: 10.1371/journal.pone.0003721. Epub 2008 Nov 13. PLoS One. 2008. PMID: 19005568 Free PMC article.

3

Cell-nonautonomous effects of dFOXO/DAF-16 in aging.

Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L. Alic N, et al. Cell Rep. 2014 Feb 27;6(4):608-16. doi: 10.1016/j.celrep.2014.01.015. Epub 2014 Feb 6. Cell Rep. 2014. PMID: 24508462 Free PMC article.

4

Insulin/IGF-like signalling, the central nervous system and aging.

Broughton S, Partridge L. Broughton S, et al. Biochem J. 2009 Feb 15;418(1):1-12. doi: 10.1042/BJ20082102. Biochem J. 2009. PMID: 19159343 Review.

5

The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila.

Ikeya T, Broughton S, Alic N, Grandison R, Partridge L. Ikeya T, et al. Proc Biol Sci. 2009 Nov 7;276(1674):3799-807. doi: 10.1098/rspb.2009.0778. Epub 2009 Aug 19. Proc Biol Sci. 2009. PMID: 19692410 Free PMC article.

6

Molecular evolution and functional characterization of Drosophila insulin-like peptides.

Grönke S, Clarke DF, Broughton S, Andrews TD, Partridge L. Grönke S, et al. PLoS Genet. 2010 Feb 26;6(2):e1000857. doi: 10.1371/journal.pgen.1000857. PLoS Genet. 2010. PMID: 20195512 Free PMC article.

7

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands.

Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, Driege Y, Martinez P, Hafen E, Withers DJ, Leevers SJ, Partridge L. Broughton SJ, et al. Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):3105-10. doi: 10.1073/pnas.0405775102. Epub 2005 Feb 11. Proc Natl Acad Sci U S A. 2005. PMID: 15708981 Free PMC article.

8

Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity.

Martínez Corrales G, Filer D, Wenz KC, Rogan A, Phillips G, Li M, Feseha Y, Broughton SJ, Alic N. Martínez Corrales G, et al. Among authors: broughton sj. Cell Rep. 2020 Feb 11;30(6):1661-1669.e4. doi: 10.1016/j.celrep.2020.01.017. Cell Rep. 2020. PMID: 32049000 Free PMC article.

9

The Drosophila insulin receptor independently modulates lifespan and locomotor senescence.

Ismail MZ, Hodges MD, Boylan M, Achall R, Shirras A, Broughton SJ. Ismail MZ, et al. Among authors: broughton sj. PLoS One. 2015 May 28;10(5):e0125312. doi: 10.1371/journal.pone.0125312. eCollection 2015. PLoS One. 2015. PMID: 26020640 Free PMC article.

10

Loss of angiotensin-converting enzyme-related (ACER) peptidase disrupts behavioural and metabolic responses to diet in Drosophila melanogaster.

Glover Z, Hodges MD, Dravecz N, Cameron J, Askwith H, Shirras A, Broughton SJ. Glover Z, et al. Among authors: broughton sj. J Exp Biol. 2019 Apr 25;222(Pt 8):jeb194332. doi: 10.1242/jeb.194332. J Exp Biol. 2019. PMID: 30940674

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