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A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication.
Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, Domené S, Vélez JI, Karkera JD, Balog J, Berg K, Kleta R, Gahl WA, Roessler E, Long R, Lie J, Pineda D, Londoño AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Johansson S, Knappskog PM, Haavik J, Ribases M, Cormand B, Bayes M, Casas M, Ramos-Quiroga JA, Hervas A, Maher BS, Faraone SV, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Swanson J, Vortmeyer A, Bailey-Wilson JE, Castellanos FX, Muenke M. Arcos-Burgos M, et al. Among authors: castellanos fx. Mol Psychiatry. 2010 Nov;15(11):1053-66. doi: 10.1038/mp.2010.6. Epub 2010 Feb 16. Mol Psychiatry. 2010. PMID: 20157310 Free article.
Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci.
Jain M, Palacio LG, Castellanos FX, Palacio JD, Pineda D, Restrepo MI, Muñoz JF, Lopera F, Wallis D, Berg K, Bailey-Wilson JE, Arcos-Burgos M, Muenke M. Jain M, et al. Among authors: castellanos fx. Biol Psychiatry. 2007 Jun 15;61(12):1329-39. doi: 10.1016/j.biopsych.2006.06.026. Epub 2006 Sep 1. Biol Psychiatry. 2007. PMID: 16950213
Polymorphisms in the neural nicotinic acetylcholine receptor α4 subunit (CHRNA4) are associated with ADHD in a genetic isolate.
Wallis D, Arcos-Burgos M, Jain M, Castellanos FX, Palacio JD, Pineda D, Lopera F, Stanescu H, Pineda D, Berg K, Palacio LG, Bailey-Wilson JE, Muenke M. Wallis D, et al. Among authors: castellanos fx. Atten Defic Hyperact Disord. 2009 May;1(1):19-24. doi: 10.1007/s12402-009-0003-5. Epub 2009 Apr 25. Atten Defic Hyperact Disord. 2009. PMID: 21432576
ADGRL3 (LPHN3) variants predict substance use disorder.
Arcos-Burgos M, Vélez JI, Martinez AF, Ribasés M, Ramos-Quiroga JA, Sánchez-Mora C, Richarte V, Roncero C, Cormand B, Fernández-Castillo N, Casas M, Lopera F, Pineda DA, Palacio JD, Acosta-López JE, Cervantes-Henriquez ML, Sánchez-Rojas MG, Puentes-Rozo PJ, Molina BSG; MTA Cooperative Group; Boden MT, Wallis D, Lidbury B, Newman S, Easteal S, Swanson J, Patel H, Volkow N, Acosta MT, Castellanos FX, de Leon J, Mastronardi CA, Muenke M. Arcos-Burgos M, et al. Among authors: castellanos fx. Transl Psychiatry. 2019 Jan 29;9(1):42. doi: 10.1038/s41398-019-0396-7. Transl Psychiatry. 2019. PMID: 30696812 Free PMC article.
A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD.
Jain M, Vélez JI, Acosta MT, Palacio LG, Balog J, Roessler E, Pineda D, Londoño AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Swanson J, Castellanos FX, Bailey-Wilson JE, Arcos-Burgos M, Muenke M. Jain M, et al. Among authors: castellanos fx. Mol Psychiatry. 2012 Jul;17(7):741-7. doi: 10.1038/mp.2011.59. Epub 2011 May 24. Mol Psychiatry. 2012. PMID: 21606926 Free PMC article.
Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate.
Mastronardi CA, Pillai E, Pineda DA, Martinez AF, Lopera F, Velez JI, Palacio JD, Patel H, Easteal S, Acosta MT, Castellanos FX, Muenke M, Arcos-Burgos M. Mastronardi CA, et al. Among authors: castellanos fx. Mol Psychiatry. 2016 Oct;21(10):1434-40. doi: 10.1038/mp.2015.172. Epub 2015 Nov 24. Mol Psychiatry. 2016. PMID: 26598068 Free PMC article.
Analysis of brain metabolism by proton magnetic resonance spectroscopy (1H-MRS) in attention-deficit/hyperactivity disorder suggests a generalized differential ontogenic pattern from controls.
Arcos-Burgos M, Londoño AC, Pineda DA, Lopera F, Palacio JD, Arbelaez A, Acosta MT, Vélez JI, Castellanos FX, Muenke M. Arcos-Burgos M, et al. Among authors: castellanos fx. Atten Defic Hyperact Disord. 2012 Dec;4(4):205-12. doi: 10.1007/s12402-012-0088-0. Epub 2012 Jul 20. Atten Defic Hyperact Disord. 2012. PMID: 23012086 Free PMC article.
356 results