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The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Heeren G, Rinnerthaler M, Laun P, von Seyerl P, Kössler S, Klinger H, Hager M, Bogengruber E, Jarolim S, Simon-Nobbe B, Schüller C, Carmona-Gutierrez D, Breitenbach-Koller L, Mück C, Jansen-Dürr P, Criollo A, Kroemer G, Madeo F, Breitenbach M. Heeren G, et al. Among authors: jarolim s. Aging (Albany NY). 2009 Jul 13;1(7):622-36. doi: 10.18632/aging.100065. Aging (Albany NY). 2009. PMID: 20157544 Free PMC article.
MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria.
Rinnerthaler M, Jarolim S, Heeren G, Palle E, Perju S, Klinger H, Bogengruber E, Madeo F, Braun RJ, Breitenbach-Koller L, Breitenbach M, Laun P. Rinnerthaler M, et al. Among authors: jarolim s. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):631-8. doi: 10.1016/j.bbabio.2006.05.022. Epub 2006 May 20. Biochim Biophys Acta. 2006. PMID: 16806052 Free article.
A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae.
Laun P, Ramachandran L, Jarolim S, Herker E, Liang P, Wang J, Weinberger M, Burhans DT, Suter B, Madeo F, Burhans WC, Breitenbach M. Laun P, et al. Among authors: jarolim s. FEMS Yeast Res. 2005 Dec;5(12):1261-72. doi: 10.1016/j.femsyr.2005.07.006. Epub 2005 Aug 31. FEMS Yeast Res. 2005. PMID: 16168721
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.
Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Timmermann B, et al. Among authors: jarolim s. Aging (Albany NY). 2010 Aug;2(8):475-86. doi: 10.18632/aging.100187. Aging (Albany NY). 2010. PMID: 20729566 Free PMC article.
Superoxide radicals have a protective role during H2O2 stress.
Thorpe GW, Reodica M, Davies MJ, Heeren G, Jarolim S, Pillay B, Breitenbach M, Higgins VJ, Dawes IW. Thorpe GW, et al. Among authors: jarolim s. Mol Biol Cell. 2013 Sep;24(18):2876-84. doi: 10.1091/mbc.E13-01-0052. Epub 2013 Jul 17. Mol Biol Cell. 2013. PMID: 23864711 Free PMC article.
Slow Growth and Increased Spontaneous Mutation Frequency in Respiratory Deficient afo1- Yeast Suppressed by a Dominant Mutation in ATP3.
Li J, Rinnerthaler M, Hartl J, Weber M, Karl T, Breitenbach-Koller H, Mülleder M, Vowinckel J, Marx H, Sauer M, Mattanovich D, Ata Ö, De S, Greslehner GP, Geltinger F, Burhans B, Grant C, Doronina V, Ralser M, Streubel MK, Grabner C, Jarolim S, Moßhammer C, Gourlay CW, Hasek J, Cullen PJ, Liti G, Ralser M, Breitenbach M. Li J, et al. Among authors: jarolim s. G3 (Bethesda). 2020 Dec 3;10(12):4637-4648. doi: 10.1534/g3.120.401537. G3 (Bethesda). 2020. PMID: 33093184 Free PMC article.
Saccharomyces cerevisiae genes involved in survival of heat shock.
Jarolim S, Ayer A, Pillay B, Gee AC, Phrakaysone A, Perrone GG, Breitenbach M, Dawes IW. Jarolim S, et al. G3 (Bethesda). 2013 Dec 9;3(12):2321-33. doi: 10.1534/g3.113.007971. G3 (Bethesda). 2013. PMID: 24142923 Free PMC article.
11 results