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The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Heeren G, Rinnerthaler M, Laun P, von Seyerl P, Kössler S, Klinger H, Hager M, Bogengruber E, Jarolim S, Simon-Nobbe B, Schüller C, Carmona-Gutierrez D, Breitenbach-Koller L, Mück C, Jansen-Dürr P, Criollo A, Kroemer G, Madeo F, Breitenbach M. Heeren G, et al. Among authors: klinger h. Aging (Albany NY). 2009 Jul 13;1(7):622-36. doi: 10.18632/aging.100065. Aging (Albany NY). 2009. PMID: 20157544 Free PMC article.
MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria.
Rinnerthaler M, Jarolim S, Heeren G, Palle E, Perju S, Klinger H, Bogengruber E, Madeo F, Braun RJ, Breitenbach-Koller L, Breitenbach M, Laun P. Rinnerthaler M, et al. Among authors: klinger h. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):631-8. doi: 10.1016/j.bbabio.2006.05.022. Epub 2006 May 20. Biochim Biophys Acta. 2006. PMID: 16806052 Free article.
Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast.
Rinnerthaler M, Büttner S, Laun P, Heeren G, Felder TK, Klinger H, Weinberger M, Stolze K, Grousl T, Hasek J, Benada O, Frydlova I, Klocker A, Simon-Nobbe B, Jansko B, Breitenbach-Koller H, Eisenberg T, Gourlay CW, Madeo F, Burhans WC, Breitenbach M. Rinnerthaler M, et al. Among authors: klinger h. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8658-63. doi: 10.1073/pnas.1201629109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586098 Free PMC article.
Protein folding diseases and neurodegeneration: lessons learned from yeast.
Winderickx J, Delay C, De Vos A, Klinger H, Pellens K, Vanhelmont T, Van Leuven F, Zabrocki P. Winderickx J, et al. Among authors: klinger h. Biochim Biophys Acta. 2008 Jul;1783(7):1381-95. doi: 10.1016/j.bbamcr.2008.01.020. Epub 2008 Feb 11. Biochim Biophys Acta. 2008. PMID: 18298958 Free article. Review.
ON/OFF non-motor evaluation: a new way to evaluate non-motor fluctuations in Parkinson's disease.
Faggianelli F, Witjas T, Azulay JP, Benatru I, Hubsch C, Anheim M, Moreau C, Hainque E, Drapier S, Jarraya B, Laurencin C, Guehl D, Hopes L, Brefel-Courbon C, Tir M, Marques A, Rouaud T, Maltete D, Giordana C, Baumstarck K, Rascol O, Corvol JC, Rolland AS, Devos D, Eusebio A; PREDISTIM study group. Faggianelli F, et al. J Neurol Neurosurg Psychiatry. 2024 Jan 25:jnnp-2023-332551. doi: 10.1136/jnnp-2023-332551. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38272656
Imbalanced motivated behaviors according to motor sign asymmetry in drug-naïve Parkinson's disease.
Béreau M, Castrioto A, Servant M, Lhommée E, Desmarets M, Bichon A, Pélissier P, Schmitt E, Klinger H, Longato N, Phillipps C, Wirth T, Fraix V, Benatru I, Durif F, Azulay JP, Moro E, Broussolle E, Thobois S, Tranchant C, Krack P, Anheim M. Béreau M, et al. Among authors: klinger h. Sci Rep. 2023 Dec 1;13(1):21234. doi: 10.1038/s41598-023-48188-0. Sci Rep. 2023. PMID: 38040775 Free PMC article.
Efficacy and safety of clonidine for the treatment of impulse control disorder in Parkinson's disease: a multicenter, parallel, randomised, double-blind, Phase 2b Clinical trial.
Laurencin C, Timestit N, Marques A, Duchez DD, Giordana C, Meoni S, Huddlestone M, Danaila T, Anheim M, Klinger H, Vidal T, Fatisson M, Caire C, Nourredine M, Boulinguez P, Dhelens C, Ballanger B, Prange S, Bin S, Thobois S. Laurencin C, et al. Among authors: klinger h. J Neurol. 2023 Oct;270(10):4851-4859. doi: 10.1007/s00415-023-11814-y. Epub 2023 Jun 20. J Neurol. 2023. PMID: 37338615 Free PMC article. Clinical Trial.
298 results