Angeles D - Search Results

1

Multiple LRRK2 variants modulate risk of Parkinson disease: a Chinese multicenter study.

Tan EK, Peng R, Teo YY, Tan LC, Angeles D, Ho P, Chen ML, Lin CH, Mao XY, Chang XL, Prakash KM, Liu JJ, Au WL, Le WD, Jankovic J, Burgunder JM, Zhao Y, Wu RM. Tan EK, et al. Among authors: angeles d. Hum Mutat. 2010 May;31(5):561-8. doi: 10.1002/humu.21225. Hum Mutat. 2010. PMID: 20186690

2

Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death.

Angeles DC, Gan BH, Onstead L, Zhao Y, Lim KL, Dachsel J, Melrose H, Farrer M, Wszolek ZK, Dickson DW, Tan EK. Angeles DC, et al. Hum Mutat. 2011 Dec;32(12):1390-7. doi: 10.1002/humu.21582. Epub 2011 Sep 12. Hum Mutat. 2011. PMID: 21850687

3

Targeting leucine-rich repeat kinase 2 in Parkinson's disease.

Chan SL, Angeles DC, Tan EK. Chan SL, et al. Expert Opin Ther Targets. 2013 Dec;17(12):1471-82. doi: 10.1517/14728222.2013.842978. Epub 2013 Nov 9. Expert Opin Ther Targets. 2013. PMID: 24206363 Review.

4

Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila.

Angeles DC, Ho P, Chua LL, Wang C, Yap YW, Ng C, Zhou Zd, Lim KL, Wszolek ZK, Wang HY, Tan EK. Angeles DC, et al. Hum Mol Genet. 2014 Jun 15;23(12):3157-65. doi: 10.1093/hmg/ddu026. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24459295 Free PMC article.

5

MAP1B rescues LRRK2 mutant-mediated cytotoxicity.

Chan SL, Chua LL, Angeles DC, Tan EK. Chan SL, et al. Mol Brain. 2014 Apr 22;7:29. doi: 10.1186/1756-6606-7-29. Mol Brain. 2014. PMID: 24754922 Free PMC article.

6

Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2.

Angeles DC, Ho P, Dymock BW, Lim KL, Zhou ZD, Tan EK. Angeles DC, et al. Ann Clin Transl Neurol. 2016 Mar 2;3(4):288-94. doi: 10.1002/acn3.282. eCollection 2016 Apr. Ann Clin Transl Neurol. 2016. PMID: 27081659 Free PMC article.

7

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

Chen ZC, Zhang W, Chua LL, Chai C, Li R, Lin L, Cao Z, Angeles DC, Stanton LW, Peng JH, Zhou ZD, Lim KL, Zeng L, Tan EK. Chen ZC, et al. Sci Signal. 2017 Jul 18;10(488):eaam6790. doi: 10.1126/scisignal.aam6790. Sci Signal. 2017. PMID: 28720718

8

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy.

Zhou ZD, Xie SP, Sathiyamoorthy S, Saw WT, Sing TY, Ng SH, Chua HP, Tang AM, Shaffra F, Li Z, Wang H, Ho PG, Lai MK, Angeles DC, Lim TM, Tan EK. Zhou ZD, et al. Hum Mol Genet. 2015 Nov 15;24(22):6314-30. doi: 10.1093/hmg/ddv340. Epub 2015 Aug 26. Hum Mol Genet. 2015. PMID: 26310625

9

LINGO1 variant increases risk of familial essential tremor.

Tan EK, Teo YY, Prakash KM, Li R, Lim HQ, Angeles D, Tan LC, Au WL, Yih Y, Zhao Y. Tan EK, et al. Among authors: angeles d. Neurology. 2009 Oct 6;73(14):1161-2. doi: 10.1212/WNL.0b013e3181bacfc9. Neurology. 2009. PMID: 19805735 Free PMC article. No abstract available.

10

Linking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD).

Zhou ZD, Sathiyamoorthy S, Angeles DC, Tan EK. Zhou ZD, et al. Mol Brain. 2016 Apr 18;9:41. doi: 10.1186/s13041-016-0218-2. Mol Brain. 2016. PMID: 27090516 Free PMC article. Review.

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