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AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression.
Kunsch C, Luchoomun J, Chen XL, Dodd GL, Karu KS, Meng CQ, Marino EM, Olliff LK, Piper JD, Qiu FH, Sikorski JA, Somers PK, Suen KL, Thomas S, Whalen AM, Wasserman MA, Sundell CL. Kunsch C, et al. J Pharmacol Exp Ther. 2005 May;313(2):492-501. doi: 10.1124/jpet.104.080804. Epub 2005 Feb 8. J Pharmacol Exp Ther. 2005. PMID: 15701708
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
Meng CQ, Somers PK, Hoong LK, Zheng XS, Ye Z, Worsencroft KJ, Simpson JE, Hotema MR, Weingarten MD, MacDOnald ML, Hill RR, Marino EM, Suen KL, Luchoomun J, Kunsch C, Landers LK, Stefanopoulos D, Howard RB, Sundell CL, Saxena U, Wasserman MA, Sikorski JA. Meng CQ, et al. Among authors: kunsch c. J Med Chem. 2004 Dec 2;47(25):6420-32. doi: 10.1021/jm049685u. J Med Chem. 2004. PMID: 15566311
Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-alpha-induced VCAM-1 expression.
Meng CQ, Zheng XS, Ni L, Ye Z, Simpson JE, Worsencroft KJ, Hotema MR, Weingarten MD, Skudlarek JW, Gilmore JM, Hoong LK, Hill RR, Marino EM, Suen KL, Kunsch C, Wasserman MA, Sikorski JA. Meng CQ, et al. Among authors: kunsch c. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1513-7. doi: 10.1016/j.bmcl.2004.01.021. Bioorg Med Chem Lett. 2004. PMID: 15006393
45 results