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101 results

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Page 1
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Liu J, He S, Jian T, Dobbelaar PH, Sebhat IK, Lin LS, Goodman A, Guo C, Guzzo PR, Hadden M, Henderson AJ, Pattamana K, Ruenz M, Sargent BJ, Swenson B, Yet L, Tamvakopoulos C, Peng Q, Pan J, Kan Y, Palyha O, Kelly TM, Guan XM, Howard AD, Marsh DJ, Metzger JM, Reitman ML, Wyvratt MJ, Nargund RP. Liu J, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2074-7. doi: 10.1016/j.bmcl.2010.02.076. Epub 2010 Feb 21. Bioorg Med Chem Lett. 2010. PMID: 20219372
A receptor in pituitary and hypothalamus that functions in growth hormone release.
Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. Howard AD, et al. Science. 1996 Aug 16;273(5277):974-7. doi: 10.1126/science.273.5277.974. Science. 1996. PMID: 8688086
Peptidomimetic regulation of growth hormone secretion.
Smith RG, Van der Ploeg LH, Howard AD, Feighner SD, Cheng K, Hickey GJ, Wyvratt MJ Jr, Fisher MH, Nargund RP, Patchett AA. Smith RG, et al. Among authors: nargund rp. Endocr Rev. 1997 Oct;18(5):621-45. doi: 10.1210/edrv.18.5.0316. Endocr Rev. 1997. PMID: 9331545 Review. No abstract available.
Tripeptide growth hormone secretagogues.
Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537
Receptor for motilin identified in the human gastrointestinal system.
Feighner SD, Tan CP, McKee KK, Palyha OC, Hreniuk DL, Pong SS, Austin CP, Figueroa D, MacNeil D, Cascieri MA, Nargund R, Bakshi R, Abramovitz M, Stocco R, Kargman S, O'Neill G, Van Der Ploeg LH, Evans J, Patchett AA, Smith RG, Howard AD. Feighner SD, et al. Science. 1999 Jun 25;284(5423):2184-8. doi: 10.1126/science.284.5423.2184. Science. 1999. PMID: 10381885
101 results