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Germline PTEN mutations are rare and highly penetrant.
Rustad CF, Bjørnslett M, Heimdal KR, Mæhle L, Apold J, Møller P. Rustad CF, et al. Among authors: bjornslett m. Hered Cancer Clin Pract. 2006 Dec 15;4(4):177-85. doi: 10.1186/1897-4287-4-4-177. Hered Cancer Clin Pract. 2006. PMID: 20223021 Free PMC article.
The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians.
Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS, Stoltenberg C, Romundstad P, Hveem K, Lillehaug JR, Vatten L, Devilee P, Dørum A, Lønning PE. Knappskog S, et al. Among authors: bjornslett m. Cancer Cell. 2011 Feb 15;19(2):273-82. doi: 10.1016/j.ccr.2010.12.019. Cancer Cell. 2011. PMID: 21316605 Free article.
Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.
Berg KCG, Eide PW, Eilertsen IA, Johannessen B, Bruun J, Danielsen SA, Bjørnslett M, Meza-Zepeda LA, Eknæs M, Lind GE, Myklebost O, Skotheim RI, Sveen A, Lothe RA. Berg KCG, et al. Among authors: bjornslett m. Mol Cancer. 2017 Jul 6;16(1):116. doi: 10.1186/s12943-017-0691-y. Mol Cancer. 2017. PMID: 28683746 Free PMC article.
Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer.
Bergsland CH, Bruun J, Guren MG, Svindland A, Bjørnslett M, Smeby J, Hektoen M, Kolberg M, Domingo E, Pellinen T, Tomlinson I, Kerr D, Church DN, Nesbakken A, Sveen A, Lothe RA. Bergsland CH, et al. Among authors: bjornslett m. ESMO Open. 2020 Nov;5(6):e001040. doi: 10.1136/esmoopen-2020-001040. ESMO Open. 2020. PMID: 33219056 Free PMC article.
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models.
Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Välimäki K, Bjørnslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T. Bruun J, et al. Among authors: bjornslett m. Mol Oncol. 2022 Jun;16(12):2312-2329. doi: 10.1002/1878-0261.13159. Epub 2021 Dec 26. Mol Oncol. 2022. PMID: 34890102 Free PMC article.
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