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Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.
Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, Fukumura D, Sorensen AG, Jain RK. Kamoun WS, et al. Among authors: sorensen ag. J Clin Oncol. 2009 May 20;27(15):2542-52. doi: 10.1200/JCO.2008.19.9356. Epub 2009 Mar 30. J Clin Oncol. 2009. PMID: 19332720 Free PMC article.
Vessel caliber--a potential MRI biomarker of tumour response in clinical trials.
Emblem KE, Farrar CT, Gerstner ER, Batchelor TT, Borra RJ, Rosen BR, Sorensen AG, Jain RK. Emblem KE, et al. Among authors: sorensen ag. Nat Rev Clin Oncol. 2014 Oct;11(10):566-84. doi: 10.1038/nrclinonc.2014.126. Epub 2014 Aug 12. Nat Rev Clin Oncol. 2014. PMID: 25113840 Free PMC article. Review.
Angiogenesis in brain tumours.
Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT. Jain RK, et al. Among authors: sorensen ag. Nat Rev Neurosci. 2007 Aug;8(8):610-22. doi: 10.1038/nrn2175. Nat Rev Neurosci. 2007. PMID: 17643088 Review.
Response criteria for glioma.
Sorensen AG, Batchelor TT, Wen PY, Zhang WT, Jain RK. Sorensen AG, et al. Nat Clin Pract Oncol. 2008 Nov;5(11):634-44. doi: 10.1038/ncponc1204. Epub 2008 Aug 19. Nat Clin Pract Oncol. 2008. PMID: 18711427 Free PMC article. Review.
A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients.
Sorensen AG, Batchelor TT, Zhang WT, Chen PJ, Yeo P, Wang M, Jennings D, Wen PY, Lahdenranta J, Ancukiewicz M, di Tomaso E, Duda DG, Jain RK. Sorensen AG, et al. Cancer Res. 2009 Jul 1;69(13):5296-300. doi: 10.1158/0008-5472.CAN-09-0814. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549889 Free PMC article.
233 results