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TLR4 is a negative regulator in noninfectious lung inflammation.
Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA. Zhao H, et al. Among authors: shen h, shen l. J Immunol. 2010 May 1;184(9):5308-14. doi: 10.4049/jimmunol.1000009. Epub 2010 Mar 31. J Immunol. 2010. PMID: 20357263 Free PMC article.
Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma.
Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA. Ochkur SI, et al. Among authors: shen h. J Immunol. 2007 Jun 15;178(12):7879-89. doi: 10.4049/jimmunol.178.12.7879. J Immunol. 2007. PMID: 17548626
Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation.
Li FF, Shen J, Shen HJ, Zhang X, Cao R, Zhang Y, Qui Q, Lin XX, Xie YC, Zhang LH, Jia YL, Dong XW, Jiang JX, Bao MJ, Zhang S, Ma WJ, Wu XM, Shen H, Xie QM, Ke Y. Li FF, et al. Among authors: shen h, shen hj, shen j. J Immunol. 2012 Sep 15;189(6):3159-67. doi: 10.4049/jimmunol.1200197. Epub 2012 Aug 13. J Immunol. 2012. PMID: 22891281 Free PMC article.
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