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A SUMO-regulated activation function controls synergy of c-Myb through a repressor-activator switch leading to differential p300 recruitment.
Nucleic Acids Res. 2010 Aug;38(15):4970-84. doi: 10.1093/nar/gkq245. Epub 2010 Apr 12.
Nucleic Acids Res. 2010.
PMID: 20385574
Free PMC article.
PIAS1 interacts with FLASH and enhances its co-activation of c-Myb.
Alm-Kristiansen AH, Lorenzo PI, Molværsmyr AK, Matre V, Ledsaak M, Sæther T, Gabrielsen OS.
Alm-Kristiansen AH, et al. Among authors: molvaersmyr ak.
Mol Cancer. 2011 Feb 21;10:21. doi: 10.1186/1476-4598-10-21.
Mol Cancer. 2011.
PMID: 21338522
Free PMC article.
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PIAS1 binds p300 and behaves as a coactivator or corepressor of the transcription factor c-Myb dependent on SUMO-status.
Ledsaak M, Bengtsen M, Molværsmyr AK, Fuglerud BM, Matre V, Eskeland R, Gabrielsen OS.
Ledsaak M, et al. Among authors: molvaersmyr ak.
Biochim Biophys Acta. 2016 May;1859(5):705-18. doi: 10.1016/j.bbagrm.2016.03.011. Epub 2016 Mar 29.
Biochim Biophys Acta. 2016.
PMID: 27032383
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