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The 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor INCB13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy.
Rosenstock J, Banarer S, Fonseca VA, Inzucchi SE, Sun W, Yao W, Hollis G, Flores R, Levy R, Williams WV, Seckl JR, Huber R; INCB13739-202 Principal Investigators. Rosenstock J, et al. Among authors: seckl jr. Diabetes Care. 2010 Jul;33(7):1516-22. doi: 10.2337/dc09-2315. Epub 2010 Apr 22. Diabetes Care. 2010. PMID: 20413513 Free PMC article. Clinical Trial.
Morning cortisol levels and cognitive abilities in people with type 2 diabetes: the Edinburgh type 2 diabetes study.
Reynolds RM, Strachan MW, Labad J, Lee AJ, Frier BM, Fowkes FG, Mitchell R, Seckl JR, Deary IJ, Walker BR, Price JF; Edinburgh Type 2 Diabetes Study Investigators. Reynolds RM, et al. Among authors: seckl jr. Diabetes Care. 2010 Apr;33(4):714-20. doi: 10.2337/dc09-1796. Epub 2010 Jan 22. Diabetes Care. 2010. PMID: 20097784 Free PMC article.
Novel fat depot-specific mechanisms underlie resistance to visceral obesity and inflammation in 11 β-hydroxysteroid dehydrogenase type 1-deficient mice.
Wamil M, Battle JH, Turban S, Kipari T, Seguret D, de Sousa Peixoto R, Nelson YB, Nowakowska D, Ferenbach D, Ramage L, Chapman KE, Hughes J, Dunbar DR, Seckl JR, Morton NM. Wamil M, et al. Among authors: seckl jr. Diabetes. 2011 Apr;60(4):1158-67. doi: 10.2337/db10-0830. Epub 2011 Feb 24. Diabetes. 2011. PMID: 21350084 Free PMC article.
460 results