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Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon.
Peyrin-Biroulet L, Beisner J, Wang G, Nuding S, Oommen ST, Kelly D, Parmentier-Decrucq E, Dessein R, Merour E, Chavatte P, Grandjean T, Bressenot A, Desreumaux P, Colombel JF, Desvergne B, Stange EF, Wehkamp J, Chamaillard M. Peyrin-Biroulet L, et al. Among authors: grandjean t. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8772-7. doi: 10.1073/pnas.0905745107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421464 Free PMC article.
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury.
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, Lemoine Y, Hot D, Chamaillard M. Normand S, et al. Among authors: grandjean t. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9601-6. doi: 10.1073/pnas.1100981108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593405 Free PMC article.
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice.
Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B. Sedhom MA, et al. Among authors: grandjean t. Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21. Gut. 2013. PMID: 23172891 Free PMC article.
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.
Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, Nùñez G, Chen G, Rosenstiel P, Chamaillard M. Couturier-Maillard A, et al. Among authors: grandjean t. J Clin Invest. 2013 Feb;123(2):700-11. doi: 10.1172/JCI62236. Epub 2013 Jan 2. J Clin Invest. 2013. PMID: 23281400 Free PMC article.
Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin.
Ubelmann F, Chamaillard M, El-Marjou F, Simon A, Netter J, Vignjevic D, Nichols BL, Quezada-Calvillo R, Grandjean T, Louvard D, Revenu C, Robine S. Ubelmann F, et al. Among authors: grandjean t. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1380-9. doi: 10.1073/pnas.1218446110. Epub 2013 Mar 21. Proc Natl Acad Sci U S A. 2013. PMID: 23520048 Free PMC article.
Pseudomonas aeruginosa type-3 secretion system dampens host defense by exploiting the NLRC4-coupled inflammasome.
Faure E, Mear JB, Faure K, Normand S, Couturier-Maillard A, Grandjean T, Balloy V, Ryffel B, Dessein R, Chignard M, Uyttenhove C, Guery B, Gosset P, Chamaillard M, Kipnis E. Faure E, et al. Among authors: grandjean t. Am J Respir Crit Care Med. 2014 Apr 1;189(7):799-811. doi: 10.1164/rccm.201307-1358OC. Am J Respir Crit Care Med. 2014. PMID: 24555512
Toll-interacting protein modulates colitis susceptibility in mice.
Maillard MH, Bega H, Uhlig HH, Barnich N, Grandjean T, Chamaillard M, Michetti P, Velin D. Maillard MH, et al. Among authors: grandjean t. Inflamm Bowel Dis. 2014 Apr;20(4):660-70. doi: 10.1097/MIB.0000000000000006. Inflamm Bowel Dis. 2014. PMID: 24572204
CCL17 production by dendritic cells is required for NOD1-mediated exacerbation of allergic asthma.
Ait Yahia S, Azzaoui I, Everaere L, Vorng H, Chenivesse C, Marquillies P, Duez C, Delacre M, Grandjean T, Balsamelli J, Fanton d'Andon M, Fan Y, Ple C, Werts C, Boneca IG, Wallaert B, Chamaillard M, Tsicopoulos A. Ait Yahia S, et al. Among authors: grandjean t. Am J Respir Crit Care Med. 2014 Apr 15;189(8):899-908. doi: 10.1164/rccm.201310-1827OC. Am J Respir Crit Care Med. 2014. PMID: 24661094
66 results