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Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon.
Peyrin-Biroulet L, Beisner J, Wang G, Nuding S, Oommen ST, Kelly D, Parmentier-Decrucq E, Dessein R, Merour E, Chavatte P, Grandjean T, Bressenot A, Desreumaux P, Colombel JF, Desvergne B, Stange EF, Wehkamp J, Chamaillard M. Peyrin-Biroulet L, et al. Among authors: wehkamp j. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8772-7. doi: 10.1073/pnas.0905745107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421464 Free PMC article.
Reduced Paneth cell alpha-defensins in ileal Crohn's disease.
Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H Jr, Fellermann K, Ganz T, Stange EF, Bevins CL. Wehkamp J, et al. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18129-34. doi: 10.1073/pnas.0505256102. Epub 2005 Dec 5. Proc Natl Acad Sci U S A. 2005. PMID: 16330776 Free PMC article.
Paneth cells and the innate immune response.
Wehkamp J, Stange EF. Wehkamp J, et al. Curr Opin Gastroenterol. 2006 Nov;22(6):644-50. doi: 10.1097/01.mog.0000245541.95408.86. Curr Opin Gastroenterol. 2006. PMID: 17053443 Review.
Crohn's disease-derived monocytes fail to induce Paneth cell defensins.
Courth LF, Ostaff MJ, Mailänder-Sánchez D, Malek NP, Stange EF, Wehkamp J. Courth LF, et al. Among authors: wehkamp j. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):14000-5. doi: 10.1073/pnas.1510084112. Epub 2015 Oct 28. Proc Natl Acad Sci U S A. 2015. PMID: 26512113 Free PMC article.
Paneth's disease.
Wehkamp J, Stange EF. Wehkamp J, et al. J Crohns Colitis. 2010 Nov;4(5):523-31. doi: 10.1016/j.crohns.2010.05.010. Epub 2010 Jul 6. J Crohns Colitis. 2010. PMID: 21122555
138 results