Schadt EE - Search Results

1

Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.

Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE. Zhong H, et al. Among authors: schadt ee. PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932. PLoS Genet. 2010. PMID: 20463879 Free PMC article.

2

Calibrating the performance of SNP arrays for whole-genome association studies.

Hao K, Schadt EE, Storey JD. Hao K, et al. Among authors: schadt ee. PLoS Genet. 2008 Jun 27;4(6):e1000109. doi: 10.1371/journal.pgen.1000109. PLoS Genet. 2008. PMID: 18584036 Free PMC article.

3

Magnitude of stratification in human populations and impacts on genome wide association studies.

Hao K, Chudin E, Greenawalt D, Schadt EE. Hao K, et al. Among authors: schadt ee. PLoS One. 2010 Jan 13;5(1):e8695. doi: 10.1371/journal.pone.0008695. PLoS One. 2010. PMID: 20084173 Free PMC article.

4

Integrating pathway analysis and genetics of gene expression for genome-wide association studies.

Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE. Zhong H, et al. Among authors: schadt ee. Am J Hum Genet. 2010 Apr 9;86(4):581-91. doi: 10.1016/j.ajhg.2010.02.020. Epub 2010 Mar 25. Am J Hum Genet. 2010. PMID: 20346437 Free PMC article.

5

An integrative genomics approach to infer causal associations between gene expression and disease.

Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, Castle J, Zhu H, Kash SF, Drake TA, Sachs A, Lusis AJ. Schadt EE, et al. Nat Genet. 2005 Jul;37(7):710-7. doi: 10.1038/ng1589. Epub 2005 Jun 19. Nat Genet. 2005. PMID: 15965475 Free PMC article.

6

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.

Lum PY, Chen Y, Zhu J, Lamb J, Melmed S, Wang S, Drake TA, Lusis AJ, Schadt EE. Lum PY, et al. Among authors: schadt ee. J Neurochem. 2006 Apr;97 Suppl 1:50-62. doi: 10.1111/j.1471-4159.2006.03661.x. J Neurochem. 2006. PMID: 16635250 Free article.

7

Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes.

Schadt EE, Lum PY. Schadt EE, et al. J Lipid Res. 2006 Dec;47(12):2601-13. doi: 10.1194/jlr.R600026-JLR200. Epub 2006 Oct 1. J Lipid Res. 2006. PMID: 17012750 Free article. Review.

8

A systems biology approach to drug discovery.

Zhu J, Zhang B, Schadt EE. Zhu J, et al. Among authors: schadt ee. Adv Genet. 2008;60:603-35. doi: 10.1016/S0065-2660(07)00421-X. Adv Genet. 2008. PMID: 18358334 Review.

9

Mapping the genetic architecture of gene expression in human liver.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R. Schadt EE, et al. PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107. PLoS Biol. 2008. PMID: 18462017 Free PMC article.

10

Advances in systems biology are enhancing our understanding of disease and moving us closer to novel disease treatments.

Schadt EE, Zhang B, Zhu J. Schadt EE, et al. Genetica. 2009 Jun;136(2):259-69. doi: 10.1007/s10709-009-9359-x. Epub 2009 Apr 11. Genetica. 2009. PMID: 19363597 Review.

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