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Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Müller-Tidow C, Klein HU, Hascher A, Isken F, Tickenbrock L, Thoennissen N, Agrawal-Singh S, Tschanter P, Disselhoff C, Wang Y, Becker A, Thiede C, Ehninger G, zur Stadt U, Koschmieder S, Seidl M, Müller FU, Schmitz W, Schlenke P, McClelland M, Berdel WE, Dugas M, Serve H; Study Alliance Leukemia. Müller-Tidow C, et al. Among authors: schlenke p. Blood. 2010 Nov 4;116(18):3564-71. doi: 10.1182/blood-2009-09-240978. Epub 2010 May 24. Blood. 2010. PMID: 20498303 Free PMC article.
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene.
Agrawal-Singh S, Isken F, Agelopoulos K, Klein HU, Thoennissen NH, Koehler G, Hascher A, Bäumer N, Berdel WE, Thiede C, Ehninger G, Becker A, Schlenke P, Wang Y, McClelland M, Krug U, Koschmieder S, Büchner T, Yu DY, Singh SV, Hansen K, Serve H, Dugas M, Müller-Tidow C. Agrawal-Singh S, et al. Among authors: schlenke p. Blood. 2012 Mar 8;119(10):2346-57. doi: 10.1182/blood-2011-06-358705. Epub 2011 Dec 29. Blood. 2012. PMID: 22207736 Free article.
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.
Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. Schoofs T, et al. Among authors: schlenke p. Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14. Blood. 2013. PMID: 23152544 Free article.
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Uttarkar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Frampton J, Klempnauer KH. Uttarkar S, et al. Among authors: schlenke p. Blood. 2016 Mar 3;127(9):1173-82. doi: 10.1182/blood-2015-09-668632. Epub 2015 Dec 2. Blood. 2016. PMID: 26631113 Free article.
MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.
Sauer T, Arteaga MF, Isken F, Rohde C, Hebestreit K, Mikesch JH, Stelljes M, Cui C, Zhou F, Göllner S, Bäumer N, Köhler G, Krug U, Thiede C, Ehninger G, Edemir B, Schlenke P, Berdel WE, Dugas M, Müller-Tidow C. Sauer T, et al. Among authors: schlenke p. Exp Hematol. 2015 Sep;43(9):794-802.e4. doi: 10.1016/j.exphem.2015.05.010. Epub 2015 Jun 11. Exp Hematol. 2015. PMID: 26072331 Free article.
An isoform-specific C/EBPβ inhibitor targets acute myeloid leukemia cells.
Jakobs A, Uttarkar S, Schomburg C, Steinmann S, Coulibaly A, Schlenke P, Berdel WE, Müller-Tidow C, Schmidt TJ, Klempnauer KH. Jakobs A, et al. Among authors: schlenke p. Leukemia. 2016 Jul;30(7):1612-5. doi: 10.1038/leu.2016.16. Epub 2016 Feb 8. Leukemia. 2016. PMID: 26854027 No abstract available.
Sex and body mass index but not CXCL12 801 G/A polymorphism determine the efficacy of hematopoietic cell mobilization: a study in healthy volunteer donors.
Lenk J, Bornhauser M, Kramer M, Hölig K, Poppe-Thiede K, Schmidt H, Wiesneth M, Schaefer-Eckart K, Schlenke P, Punzel M, Martin S, Kroschinsky F, Schmidt AH, Ehninger G, Thiede C. Lenk J, et al. Among authors: schlenke p. Biol Blood Marrow Transplant. 2013 Oct;19(10):1517-21. doi: 10.1016/j.bbmt.2013.07.018. Epub 2013 Jul 23. Biol Blood Marrow Transplant. 2013. PMID: 23891749 Free article.
157 results