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Page 1
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI. Sagoo P, et al. Among authors: hilton r. J Clin Invest. 2010 Jun;120(6):1848-61. doi: 10.1172/JCI39922. Epub 2010 May 24. J Clin Invest. 2010. PMID: 20501943 Free PMC article.
BK virus nephropathy in renal transplant patients in London.
White LH, Casian A, Hilton R, Macphee IA, Marsh J, Sweny P, Trevitt R, Frankel AH, Warrens AN; Pan-Thames Renal Audit Group. White LH, et al. Among authors: hilton r. Transplantation. 2008 Apr 15;85(7):1008-15. doi: 10.1097/TP.0b013e31816a32fc. Transplantation. 2008. PMID: 18408582
Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.
Afzali B, Edozie FC, Fazekasova H, Scottà C, Mitchell PJ, Canavan JB, Kordasti SY, Chana PS, Ellis R, Lord GM, John S, Hilton R, Lechler RI, Lombardi G. Afzali B, et al. Among authors: hilton r. Clin J Am Soc Nephrol. 2013 Aug;8(8):1396-405. doi: 10.2215/CJN.12931212. Epub 2013 Apr 11. Clin J Am Soc Nephrol. 2013. PMID: 23580782 Free PMC article.
Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial.
Dorling A, Rebollo-Mesa I, Hilton R, Peacock JL, Vaughan R, Gardner L, Danzi G, Baker R, Clark B, Thuraisingham RC, Buckland M, Picton M, Martin S, Borrows R, Briggs D, Horne R, McCrone P, Kelly J, Murphy C. Dorling A, et al. Among authors: hilton r. Trials. 2014 Jan 21;15:30. doi: 10.1186/1745-6215-15-30. Trials. 2014. PMID: 24447519 Free PMC article. Clinical Trial.
Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?
Rebollo-Mesa I, Nova-Lamperti E, Mobillo P, Runglall M, Christakoudi S, Norris S, Smallcombe N, Kamra Y, Hilton R; Indices of Tolerance EU Consortium; Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks S, Macphee I, McKane W, Mohaupt MG, Pararajasingam R, Kon SP, Serón D, Sinha MD, Tucker B, Viklický O, Lechler RI, Lord GM, Hernandez-Fuentes MP. Rebollo-Mesa I, et al. Among authors: hilton r. Am J Transplant. 2016 Dec;16(12):3443-3457. doi: 10.1111/ajt.13932. Epub 2016 Aug 8. Am J Transplant. 2016. PMID: 27328267 Free PMC article.
Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.
Christakoudi S, Runglall M, Mobillo P, Rebollo-Mesa I, Tsui TL, Nova-Lamperti E, Norris S, Kamra Y, Hilton R, Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks SD, Macphee I, McKane W, Mohaupt MG, Pararajasingam R, Kon SP, Serón D, Sinha M, Tucker B, Viklický O, Lechler RI, Lord GM, Stahl D, Hernandez-Fuentes MP. Christakoudi S, et al. Among authors: hilton r. Mol Cell Endocrinol. 2018 Sep 15;473:205-216. doi: 10.1016/j.mce.2018.01.021. Epub 2018 Feb 7. Mol Cell Endocrinol. 2018. PMID: 29427591 Free article.
A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials.
Fraser H, Safinia N, Grageda N, Thirkell S, Lowe K, Fry LJ, Scottá C, Hope A, Fisher C, Hilton R, Game D, Harden P, Bushell A, Wood K, Lechler RI, Lombardi G. Fraser H, et al. Among authors: hilton r. Mol Ther Methods Clin Dev. 2018 Jan 31;8:198-209. doi: 10.1016/j.omtm.2018.01.006. eCollection 2018 Mar 16. Mol Ther Methods Clin Dev. 2018. PMID: 29552576 Free PMC article.
Update to the study protocol, including statistical analysis plan, for the multicentre, randomised controlled OuTSMART trial: a combined screening/treatment programme to prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies.
Stringer D, Gardner LM, Peacock JL, Rebollo-Mesa I, Hilton R, Shaw O, Baker R, Clark B, Thuraisingham RC, Buckland M, Picton M, Worthington J, Borrows R, Briggs D, Shah S, Shiu KY, McCullough K, Phanish M, Hegarty J, Stoves J, Ahmed A, Ayub W, Horne R, McCrone P, Kelly J, Murphy C, Dorling A. Stringer D, et al. Among authors: hilton r. Trials. 2019 Aug 5;20(1):476. doi: 10.1186/s13063-019-3602-2. Trials. 2019. PMID: 31383029 Free PMC article.
Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Sawitzki B, et al. Among authors: hilton r. Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. Lancet. 2020. PMID: 32446407 Free PMC article.
Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy.
Christakoudi S, Runglall M, Mobillo P, Rebollo-Mesa I, Tsui TL, Nova-Lamperti E, Taube C, Norris S, Kamra Y, Hilton R, Augustine T, Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks SD, MacPhee I, McKane W, Mohaupt MG, Paz-Artal E, Kon SP, Serón D, Sinha MD, Tucker B, Viklický O, Stahl D, Lechler RI, Lord GM, Hernandez-Fuentes MP. Christakoudi S, et al. Among authors: hilton r. EBioMedicine. 2020 Aug;58:102899. doi: 10.1016/j.ebiom.2020.102899. Epub 2020 Jul 21. EBioMedicine. 2020. PMID: 32707447 Free PMC article.
196 results