Ogihara T - Search Results

1

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

Maier B, Ogihara T, Trace AP, Tersey SA, Robbins RD, Chakrabarti SK, Nunemaker CS, Stull ND, Taylor CA, Thompson JE, Dondero RS, Lewis EC, Dinarello CA, Nadler JL, Mirmira RG. Maier B, et al. Among authors: ogihara t. J Clin Invest. 2010 Jun;120(6):2156-70. doi: 10.1172/JCI38924. Epub 2010 May 24. J Clin Invest. 2010. PMID: 20501948 Free PMC article.

2

An islet in distress: β cell failure in type 2 diabetes.

Ogihara T, Mirmira RG. Ogihara T, et al. J Diabetes Investig. 2010 Aug 2;1(4):123-33. doi: 10.1111/j.2040-1124.2010.00021.x. J Diabetes Investig. 2010. PMID: 24843420 Free PMC article. Review.

3

SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell.

Fujimaki K, Ogihara T, Morris DL, Oda H, Iida H, Fujitani Y, Mirmira RG, Evans-Molina C, Watada H. Fujimaki K, et al. Among authors: ogihara t. J Biol Chem. 2015 Jul 3;290(27):16607-18. doi: 10.1074/jbc.M115.661777. Epub 2015 May 20. J Biol Chem. 2015. PMID: 25995453 Free PMC article.

4

Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes.

Robbins RD, Tersey SA, Ogihara T, Gupta D, Farb TB, Ficorilli J, Bokvist K, Maier B, Mirmira RG. Robbins RD, et al. Among authors: ogihara t. J Biol Chem. 2010 Dec 17;285(51):39943-52. doi: 10.1074/jbc.M110.170142. Epub 2010 Oct 18. J Biol Chem. 2010. PMID: 20956533 Free PMC article.

5

Expression and function of Set7/9 in pancreatic islets.

Ogihara T, Vanderford NL, Maier B, Stein RW, Mirmira RG. Ogihara T, et al. Islets. 2009 Nov-Dec;1(3):269-72. doi: 10.4161/isl.1.3.9779. Islets. 2009. PMID: 21099283 Free PMC article.

6

Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes.

Deering TG, Ogihara T, Trace AP, Maier B, Mirmira RG. Deering TG, et al. Among authors: ogihara t. Diabetes. 2009 Jan;58(1):185-93. doi: 10.2337/db08-1150. Epub 2008 Nov 4. Diabetes. 2009. PMID: 18984737 Free PMC article.

7

Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.

Ogihara T, Chuang JC, Vestermark GL, Garmey JC, Ketchum RJ, Huang X, Brayman KL, Thorner MO, Repa JJ, Mirmira RG, Evans-Molina C. Ogihara T, et al. J Biol Chem. 2010 Feb 19;285(8):5392-404. doi: 10.1074/jbc.M109.064659. Epub 2009 Dec 11. J Biol Chem. 2010. PMID: 20007976 Free PMC article.

8

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Raum JC, et al. Among authors: ogihara t. Mol Cell Biol. 2010 Sep;30(17):4234-44. doi: 10.1128/MCB.01396-09. Epub 2010 Jun 28. Mol Cell Biol. 2010. PMID: 20584984 Free PMC article.

9

PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress.

Kono T, Ahn G, Moss DR, Gann L, Zarain-Herzberg A, Nishiki Y, Fueger PT, Ogihara T, Evans-Molina C. Kono T, et al. Among authors: ogihara t. Mol Endocrinol. 2012 Feb;26(2):257-71. doi: 10.1210/me.2011-1181. Epub 2012 Jan 12. Mol Endocrinol. 2012. PMID: 22240811 Free PMC article.

10

The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance.

Tamaki M, Fujitani Y, Hara A, Uchida T, Tamura Y, Takeno K, Kawaguchi M, Watanabe T, Ogihara T, Fukunaka A, Shimizu T, Mita T, Kanazawa A, Imaizumi MO, Abe T, Kiyonari H, Hojyo S, Fukada T, Kawauchi T, Nagamatsu S, Hirano T, Kawamori R, Watada H. Tamaki M, et al. Among authors: ogihara t. J Clin Invest. 2013 Oct;123(10):4513-24. doi: 10.1172/JCI68807. Epub 2013 Sep 24. J Clin Invest. 2013. PMID: 24051378 Free PMC article.

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