Morandi A - Search Results

1

Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance.

Plaza-Menacho I, Morandi A, Robertson D, Pancholi S, Drury S, Dowsett M, Martin LA, Isacke CM. Plaza-Menacho I, et al. Among authors: morandi a. Oncogene. 2010 Aug 19;29(33):4648-57. doi: 10.1038/onc.2010.209. Epub 2010 Jun 7. Oncogene. 2010. PMID: 20531297

2

RET in breast cancer: functional and therapeutic implications.

Morandi A, Plaza-Menacho I, Isacke CM. Morandi A, et al. Trends Mol Med. 2011 Mar;17(3):149-57. doi: 10.1016/j.molmed.2010.12.007. Epub 2011 Jan 19. Trends Mol Med. 2011. PMID: 21251878 Review.

3

Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism.

Plaza-Menacho I, Morandi A, Mologni L, Boender P, Gambacorti-Passerini C, Magee AI, Hofstra RM, Knowles P, McDonald NQ, Isacke CM. Plaza-Menacho I, et al. Among authors: morandi a. J Biol Chem. 2011 May 13;286(19):17292-302. doi: 10.1074/jbc.M110.168500. Epub 2011 Mar 22. J Biol Chem. 2011. PMID: 21454698 Free PMC article.

4

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.

Morandi A, Martin LA, Gao Q, Pancholi S, Mackay A, Robertson D, Zvelebil M, Dowsett M, Plaza-Menacho I, Isacke CM. Morandi A, et al. Cancer Res. 2013 Jun 15;73(12):3783-95. doi: 10.1158/0008-5472.CAN-12-4265. Epub 2013 May 6. Cancer Res. 2013. PMID: 23650283 Free PMC article.

5

Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase.

Mologni L, Redaelli S, Morandi A, Plaza-Menacho I, Gambacorti-Passerini C. Mologni L, et al. Among authors: morandi a. Mol Cell Endocrinol. 2013 Sep 5;377(1-2):1-6. doi: 10.1016/j.mce.2013.06.025. Epub 2013 Jun 27. Mol Cell Endocrinol. 2013. PMID: 23811235

6

Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells.

Barbetti V, Morandi A, Tusa I, Digiacomo G, Riverso M, Marzi I, Cipolleschi MG, Bessi S, Giannini A, Di Leo A, Dello Sbarba P, Rovida E. Barbetti V, et al. Among authors: morandi a. Oncogene. 2014 Aug 21;33(34):4359-64. doi: 10.1038/onc.2013.542. Epub 2013 Dec 23. Oncogene. 2014. PMID: 24362524 Free PMC article.

7

Targeting RET-interleukin-6 crosstalk to impair metastatic dissemination in breast cancer.

Morandi A, Isacke CM. Morandi A, et al. Breast Cancer Res. 2014 Jan 28;16(1):301. doi: 10.1186/bcr3608. Breast Cancer Res. 2014. PMID: 24467886 Free PMC article.

8

miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors.

Bacci M, Giannoni E, Fearns A, Ribas R, Gao Q, Taddei ML, Pintus G, Dowsett M, Isacke CM, Martin LA, Chiarugi P, Morandi A. Bacci M, et al. Among authors: morandi a. Cancer Res. 2016 Mar 15;76(6):1615-26. doi: 10.1158/0008-5472.CAN-15-2038. Epub 2016 Jan 21. Cancer Res. 2016. PMID: 26795347

9

Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts.

Andreucci E, Francica P, Fearns A, Martin LA, Chiarugi P, Isacke CM, Morandi A. Andreucci E, et al. Among authors: morandi a. Oncotarget. 2016 Dec 6;7(49):80543-80553. doi: 10.18632/oncotarget.11826. Oncotarget. 2016. PMID: 27602955 Free PMC article.

10

Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer.

Bacci M, Lorito N, Ippolito L, Ramazzotti M, Luti S, Romagnoli S, Parri M, Bianchini F, Cappellesso F, Virga F, Gao Q, Simões BM, Marangoni E, Martin LA, Comito G, Ferracin M, Giannoni E, Mazzone M, Chiarugi P, Morandi A. Bacci M, et al. Among authors: morandi a. Cell Rep. 2019 Jul 2;28(1):104-118.e8. doi: 10.1016/j.celrep.2019.06.010. Cell Rep. 2019. PMID: 31269432 Free PMC article.

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