Miller LJ - Search Results

1

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

Koole C, Wootten D, Simms J, Valant C, Sridhar R, Woodman OL, Miller LJ, Summers RJ, Christopoulos A, Sexton PM. Koole C, et al. Among authors: miller lj. Mol Pharmacol. 2010 Sep;78(3):456-65. doi: 10.1124/mol.110.065664. Epub 2010 Jun 14. Mol Pharmacol. 2010. PMID: 20547734 Free PMC article.

2

Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling.

Pham V, Dong M, Wade JD, Miller LJ, Morton CJ, Ng HL, Parker MW, Sexton PM. Pham V, et al. Among authors: miller lj. J Biol Chem. 2005 Aug 5;280(31):28610-22. doi: 10.1074/jbc.M503272200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15929987 Free article.

3

Constitutive formation of oligomeric complexes between family B G protein-coupled vasoactive intestinal polypeptide and secretin receptors.

Harikumar KG, Morfis MM, Lisenbee CS, Sexton PM, Miller LJ. Harikumar KG, et al. Among authors: miller lj. Mol Pharmacol. 2006 Jan;69(1):363-73. doi: 10.1124/mol.105.015776. Epub 2005 Oct 21. Mol Pharmacol. 2006. PMID: 16244179

4

Molecular approximations between residues 21 and 23 of secretin and its receptor: development of a model for peptide docking with the amino terminus of the secretin receptor.

Dong M, Lam PC, Gao F, Hosohata K, Pinon DI, Sexton PM, Abagyan R, Miller LJ. Dong M, et al. Among authors: miller lj. Mol Pharmacol. 2007 Aug;72(2):280-90. doi: 10.1124/mol.107.035402. Epub 2007 May 2. Mol Pharmacol. 2007. PMID: 17475809

5

Fluorescence resonance energy transfer analysis of secretin docking to its receptor: mapping distances between residues distributed throughout the ligand pharmacophore and distinct receptor residues.

Harikumar KG, Lam PC, Dong M, Sexton PM, Abagyan R, Miller LJ. Harikumar KG, et al. Among authors: miller lj. J Biol Chem. 2007 Nov 9;282(45):32834-43. doi: 10.1074/jbc.M704563200. Epub 2007 Sep 7. J Biol Chem. 2007. PMID: 17827151 Free article.

6

Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor.

Harikumar KG, Morfis MM, Sexton PM, Miller LJ. Harikumar KG, et al. Among authors: miller lj. J Mol Neurosci. 2008 Nov;36(1-3):279-85. doi: 10.1007/s12031-008-9060-z. Epub 2008 Apr 10. J Mol Neurosci. 2008. PMID: 18401761 Free PMC article.

7

Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding.

Dong M, Lam PC, Pinon DI, Sexton PM, Abagyan R, Miller LJ. Dong M, et al. Among authors: miller lj. Mol Pharmacol. 2008 Aug;74(2):413-22. doi: 10.1124/mol.108.047209. Epub 2008 May 8. Mol Pharmacol. 2008. PMID: 18467541 Free PMC article.

8

Benzodiazepine ligands can act as allosteric modulators of the Type 1 cholecystokinin receptor.

Gao F, Sexton PM, Christopoulos A, Miller LJ. Gao F, et al. Among authors: miller lj. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4401-4. doi: 10.1016/j.bmcl.2008.06.053. Epub 2008 Jun 20. Bioorg Med Chem Lett. 2008. PMID: 18621527 Free PMC article.

9

Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor.

Gao F, Harikumar KG, Dong M, Lam PC, Sexton PM, Christopoulos A, Bordner A, Abagyan R, Miller LJ. Gao F, et al. Among authors: miller lj. Mol Pharmacol. 2009 Aug;76(2):264-74. doi: 10.1124/mol.109.055756. Epub 2009 May 8. Mol Pharmacol. 2009. PMID: 19429716 Free PMC article.

10

Homology modeling of GPCRs.

Simms J, Hall NE, Lam PH, Miller LJ, Christopoulos A, Abagyan R, Sexton PM. Simms J, et al. Among authors: miller lj. Methods Mol Biol. 2009;552:97-113. doi: 10.1007/978-1-60327-317-6_7. Methods Mol Biol. 2009. PMID: 19513644

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