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Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.
Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, Dai D, Zhao Y, Hirst M, Verchere CB, Helgason CD, Marra MA, Jones SJ, Hoodless PA. Hoffman BG, et al. Among authors: lee s. Genome Res. 2010 Aug;20(8):1037-51. doi: 10.1101/gr.104356.109. Epub 2010 Jun 15. Genome Res. 2010. PMID: 20551221 Free PMC article.
Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation.
Alder O, Cullum R, Lee S, Kan AC, Wei W, Yi Y, Garside VC, Bilenky M, Griffith M, Morrissy AS, Robertson GA, Thiessen N, Zhao Y, Chen Q, Pan D, Jones SJM, Marra MA, Hoodless PA. Alder O, et al. Among authors: lee s. Cell Rep. 2014 Oct 9;9(1):261-271. doi: 10.1016/j.celrep.2014.08.046. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263553 Free PMC article.
De novo assembly and analysis of RNA-seq data.
Robertson G, Schein J, Chiu R, Corbett R, Field M, Jackman SD, Mungall K, Lee S, Okada HM, Qian JQ, Griffith M, Raymond A, Thiessen N, Cezard T, Butterfield YS, Newsome R, Chan SK, She R, Varhol R, Kamoh B, Prabhu AL, Tam A, Zhao Y, Moore RA, Hirst M, Marra MA, Jones SJ, Hoodless PA, Birol I. Robertson G, et al. Among authors: lee s. Nat Methods. 2010 Nov;7(11):909-12. doi: 10.1038/nmeth.1517. Epub 2010 Oct 10. Nat Methods. 2010. PMID: 20935650
Targeted protein degradation systems to enhance Wnt signaling.
Sampathkumar P, Jung H, Chen H, Zhang Z, Suen N, Yang Y, Huang Z, Lopez T, Benisch R, Lee SJ, Ye J, Yeh WC, Li Y. Sampathkumar P, et al. Among authors: lee sj. Elife. 2024 Jun 7;13:RP93908. doi: 10.7554/eLife.93908. Elife. 2024. PMID: 38847394
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