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Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Baker D, Pryce G, Visintin C, Sisay S, Bondarenko AI, Vanessa Ho WS, Jackson SJ, Williams TE, Al-Izki S, Sevastou I, Okuyama M, Graier WF, Stevenson LA, Tanner C, Ross R, Pertwee RG, Henstridge CM, Irving AJ, Schulman J, Powell K, Baker MD, Giovannoni G, Selwood DL. Baker D, et al. Among authors: irving aj. Br J Pharmacol. 2017 Aug;174(16):2662-2681. doi: 10.1111/bph.13889. Epub 2017 Jul 7. Br J Pharmacol. 2017. PMID: 28677901 Free PMC article. Clinical Trial.
GPR55 ligands promote receptor coupling to multiple signalling pathways.
Henstridge CM, Balenga NA, Schröder R, Kargl JK, Platzer W, Martini L, Arthur S, Penman J, Whistler JL, Kostenis E, Waldhoer M, Irving AJ. Henstridge CM, et al. Among authors: irving aj. Br J Pharmacol. 2010 Jun;160(3):604-14. doi: 10.1111/j.1476-5381.2009.00625.x. Epub 2010 Feb 5. Br J Pharmacol. 2010. PMID: 20136841 Free PMC article.
88 results