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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial.
Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, Weitzel JN, Friedlander M, Arun B, Loman N, Schmutzler RK, Wardley A, Mitchell G, Earl H, Wickens M, Carmichael J. Tutt A, et al. Among authors: wickens m. Lancet. 2010 Jul 24;376(9737):235-44. doi: 10.1016/S0140-6736(10)60892-6. Epub 2010 Jul 6. Lancet. 2010. PMID: 20609467 Clinical Trial.
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial.
Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell-McGuinn KM, Scott C, Weitzel JN, Oaknin A, Loman N, Lu K, Schmutzler RK, Matulonis U, Wickens M, Tutt A. Audeh MW, et al. Among authors: wickens m. Lancet. 2010 Jul 24;376(9737):245-51. doi: 10.1016/S0140-6736(10)60893-8. Epub 2010 Jul 6. Lancet. 2010. PMID: 20609468 Clinical Trial.
Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer.
Kaye SB, Lubinski J, Matulonis U, Ang JE, Gourley C, Karlan BY, Amnon A, Bell-McGuinn KM, Chen LM, Friedlander M, Safra T, Vergote I, Wickens M, Lowe ES, Carmichael J, Kaufman B. Kaye SB, et al. Among authors: wickens m. J Clin Oncol. 2012 Feb 1;30(4):372-9. doi: 10.1200/JCO.2011.36.9215. Epub 2011 Dec 27. J Clin Oncol. 2012. PMID: 22203755 Clinical Trial.
Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.
Storey RF, Melissa Thornton S, Lawrance R, Husted S, Wickens M, Emanuelsson H, Cannon CP, Heptinstall S, Armstrong M. Storey RF, et al. Among authors: wickens m. Platelets. 2009 Aug;20(5):341-8. doi: 10.1080/09537100903075324. Platelets. 2009. PMID: 19637098 Clinical Trial.
Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes.
Storey RF, Husted S, Harrington RA, Heptinstall S, Wilcox RG, Peters G, Wickens M, Emanuelsson H, Gurbel P, Grande P, Cannon CP. Storey RF, et al. Among authors: wickens m. J Am Coll Cardiol. 2007 Nov 6;50(19):1852-6. doi: 10.1016/j.jacc.2007.07.058. Epub 2007 Oct 23. J Am Coll Cardiol. 2007. PMID: 17980251 Free article. Clinical Trial.
Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib in two randomized, double-blind, placebo-controlled studies.
Michael Hill C, Sindet-Pederson S, Seymour RA, Hawkesford JE 2nd, Coulthard P, Lamey PJ, Gerry Cowan C, Wickens M, Jeppsson L, Dean AD, Svensson O. Michael Hill C, et al. Among authors: wickens m. Clin Ther. 2006 Sep;28(9):1279-95. doi: 10.1016/j.clinthera.2006.09.015. Clin Ther. 2006. PMID: 17062301 Clinical Trial.
Cost-benefit analysis of ecosystem modeling to support fisheries management.
Holden MH, Plagányi EE, Fulton EA, Campbell AB, Janes R, Lovett RA, Wickens M, Adams MP, Botelho LL, Dichmont CM, Erm P, Helmstedt KJ, Heneghan RF, Mendiolar M, Richardson AJ, Rogers JGD, Saunders K, Timms L. Holden MH, et al. Among authors: wickens m. J Fish Biol. 2024 Mar 30. doi: 10.1111/jfb.15741. Online ahead of print. J Fish Biol. 2024. PMID: 38553910
Evaluation of Quantitative Pupillometry in Acute Postinjury Pediatric Concussion.
Heyming T, Knudsen-Robbins C, Schomberg J, Hayakawa J, Lara B, Bacon K, Valdez B, Wickens M, Shelton SK, Romain J, Wallace E, Taraman S, Loudon W, Pearson R. Heyming T, et al. Among authors: wickens m. Pediatr Neurol. 2024 Apr;153:103-112. doi: 10.1016/j.pediatrneurol.2024.01.016. Epub 2024 Jan 14. Pediatr Neurol. 2024. PMID: 38367484
185 results