Nargund RP - Search Results

1

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.

Guo L, Ye Z, Liu J, He S, Bakshi RK, Sebhat IK, Dobbelaar PH, Hong Q, Jian T, Dellureficio JP, Tsou NN, Ball RG, Weinberg DH, MacNeil T, Tang R, Tamvakopoulos C, Peng Q, Chen HY, Chen AS, Martin WJ, MacIntyre DE, Strack AM, Fong TM, Wyvratt MJ, Nargund RP. Guo L, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4895-900. doi: 10.1016/j.bmcl.2010.06.068. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20621473

2

Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland.

Smith RG, Pong SS, Hickey G, Jacks T, Cheng K, Leonard R, Cohen CJ, Arena JP, Chang CH, Drisko J, Wyvratt M, Fisher M, Nargund R, Patchett A. Smith RG, et al. Recent Prog Horm Res. 1996;51:261-85; discussion 285-6. Recent Prog Horm Res. 1996. PMID: 8701083 Review.

3

Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine.

Chang CH, Rickes EL, McGuire L, Frazier E, Chen H, Barakat K, Nargund R, Patchett A, Smith RG, Hickey GJ. Chang CH, et al. Endocrinology. 1996 Nov;137(11):4851-6. doi: 10.1210/endo.137.11.8895356. Endocrinology. 1996. PMID: 8895356

4

MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles.

Jacks T, Smith R, Judith F, Schleim K, Frazier E, Chen H, Krupa D, Hora D Jr, Nargund R, Patchett A, Hickey G. Jacks T, et al. Endocrinology. 1996 Dec;137(12):5284-9. doi: 10.1210/endo.137.12.8940347. Endocrinology. 1996. PMID: 8940347

5

Repeat administration of the GH secretagogue MK-0677 increases and maintains elevated IGF-I levels in beagles.

Hickey GJ, Jacks TM, Schleim KD, Frazier E, Chen HY, Krupa D, Feeney W, Nargund RP, Patchett AA, Smith RG. Hickey GJ, et al. Among authors: nargund rp. J Endocrinol. 1997 Feb;152(2):183-92. doi: 10.1677/joe.0.1520183. J Endocrinol. 1997. PMID: 9071975

6

Peptidomimetic regulation of growth hormone secretion.

Smith RG, Van der Ploeg LH, Howard AD, Feighner SD, Cheng K, Hickey GJ, Wyvratt MJ Jr, Fisher MH, Nargund RP, Patchett AA. Smith RG, et al. Among authors: nargund rp. Endocr Rev. 1997 Oct;18(5):621-45. doi: 10.1210/edrv.18.5.0316. Endocr Rev. 1997. PMID: 9331545 Review. No abstract available.

7

Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.

Nargund RP, Patchett AA, Bach MA, Murphy MG, Smith RG. Nargund RP, et al. J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o. J Med Chem. 1998. PMID: 9703459 Review. No abstract available.

8

Tripeptide growth hormone secretagogues.

Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537

9

Synthesis and biological activities of phenyl piperazine-based peptidomimetic growth hormone secretagogues.

Barakat KJ, Cheng K, Chan WW, Butler BS, Jacks TM, Schleim KD, Hora DF Jr, Hickey GJ, Smith RG, Patchett AA, Nargund RP. Barakat KJ, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1431-6. doi: 10.1016/s0960-894x(98)00238-8. Bioorg Med Chem Lett. 1998. PMID: 9871779

10

Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.

Ye Z, Gao Y, Bakshi RK, Chen MH, Rohrer SP, Feighner SD, Pong SS, Howard AD, Blake A, Birzin ET, Locco L, Parmar RM, Chan WW, Schaeffer JM, Smith RG, Patchett AA, Nargund RP. Ye Z, et al. Among authors: nargund rp. Bioorg Med Chem Lett. 2000 Jan 3;10(1):5-8. doi: 10.1016/s0960-894x(99)00584-3. Bioorg Med Chem Lett. 2000. PMID: 10636230

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