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A novel pathway regulates memory and plasticity via SIRT1 and miR-134.
Gao J, Wang WY, Mao YW, Gräff J, Guan JS, Pan L, Mak G, Kim D, Su SC, Tsai LH. Gao J, et al. Among authors: tsai lh. Nature. 2010 Aug 26;466(7310):1105-9. doi: 10.1038/nature09271. Epub 2010 Jul 11. Nature. 2010. PMID: 20622856 Free PMC article.
A hippocampal Cdk5 pathway regulates extinction of contextual fear.
Sananbenesi F, Fischer A, Wang X, Schrick C, Neve R, Radulovic J, Tsai LH. Sananbenesi F, et al. Among authors: tsai lh. Nat Neurosci. 2007 Aug;10(8):1012-9. doi: 10.1038/nn1943. Epub 2007 Jul 15. Nat Neurosci. 2007. PMID: 17632506 Free PMC article.
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.
Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH. Kim D, et al. Among authors: tsai lh. Neuron. 2008 Dec 10;60(5):803-17. doi: 10.1016/j.neuron.2008.10.015. Neuron. 2008. PMID: 19081376 Free PMC article.
HDAC2 negatively regulates memory formation and synaptic plasticity.
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH. Guan JS, et al. Among authors: tsai lh. Nature. 2009 May 7;459(7243):55-60. doi: 10.1038/nature07925. Nature. 2009. PMID: 19424149 Free PMC article.
411 results