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Page 1
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA, Hodivala-Dilke KM. da Silva RG, et al. Among authors: kostourou v. Am J Pathol. 2010 Sep;177(3):1534-48. doi: 10.2353/ajpath.2010.100043. Epub 2010 Jul 16. Am J Pathol. 2010. PMID: 20639457 Free PMC article.
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Reynolds AR, Hart IR, Watson AR, Welti JC, Silva RG, Robinson SD, Da Violante G, Gourlaouen M, Salih M, Jones MC, Jones DT, Saunders G, Kostourou V, Perron-Sierra F, Norman JC, Tucker GC, Hodivala-Dilke KM. Reynolds AR, et al. Among authors: kostourou v. Nat Med. 2009 Apr;15(4):392-400. doi: 10.1038/nm.1941. Epub 2009 Mar 22. Nat Med. 2009. PMID: 19305413
Endothelial FAK is required for tumour angiogenesis.
Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M, Hodivala-Dilke KM. Tavora B, et al. Among authors: kostourou v. EMBO Mol Med. 2010 Dec;2(12):516-28. doi: 10.1002/emmm.201000106. EMBO Mol Med. 2010. PMID: 21154724 Free PMC article.
Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.
Pedrosa AR, Bodrug N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM, Kostourou V, Alexopoulou AN, Batista S, Tavora B, Serrels B, Parsons M, Iskratsch T, Hodivala-Dilke KM. Pedrosa AR, et al. Among authors: kostourou v. Cancer Res. 2019 Sep 1;79(17):4371-4386. doi: 10.1158/0008-5472.CAN-18-3934. Epub 2019 Jun 12. Cancer Res. 2019. PMID: 31189647
Regulation of lymphatic-blood vessel separation by endothelial Rac1.
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V, Hodivala-Dilke KM. D'Amico G, et al. Among authors: kostourou v. Development. 2009 Dec;136(23):4043-53. doi: 10.1242/dev.035014. Development. 2009. PMID: 19906871 Free PMC article.
FAK-heterozygous mice display enhanced tumour angiogenesis.
Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K. Kostourou V, et al. Nat Commun. 2013;4:2020. doi: 10.1038/ncomms3020. Nat Commun. 2013. PMID: 23799510 Free PMC article.
Generation of point-mutant FAK knockin mice.
Tavora B, Batista S, Alexopoulou AN, Kostourou V, Fernandez I, Robinson SD, Lees DM, Serrels B, Hodivala-Dilke K. Tavora B, et al. Among authors: kostourou v. Genesis. 2014 Nov;52(11):907-15. doi: 10.1002/dvg.22823. Epub 2014 Sep 30. Genesis. 2014. PMID: 25242698
29 results