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Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types.
Wilkerson MD, Yin X, Hoadley KA, Liu Y, Hayward MC, Cabanski CR, Muldrew K, Miller CR, Randell SH, Socinski MA, Parsons AM, Funkhouser WK, Lee CB, Roberts PJ, Thorne L, Bernard PS, Perou CM, Hayes DN. Wilkerson MD, et al. Among authors: roberts pj. Clin Cancer Res. 2010 Oct 1;16(19):4864-75. doi: 10.1158/1078-0432.CCR-10-0199. Epub 2010 Jul 19. Clin Cancer Res. 2010. PMID: 20643781 Free PMC article.
Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.
Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RR, Mullins M, Yin X, Miller CR, Thorne LB, Geiersbach KB, Muldrew KL, Funkhouser WK, Fan C, Hayward MC, Bayer S, Perou CM, Bernard PS. Wilkerson MD, et al. Among authors: roberts pj. J Mol Diagn. 2013 Jul;15(4):485-97. doi: 10.1016/j.jmoldx.2013.03.007. Epub 2013 May 20. J Mol Diagn. 2013. PMID: 23701907 Free PMC article.
Predicting drug responsiveness in human cancers using genetically engineered mice.
Usary J, Zhao W, Darr D, Roberts PJ, Liu M, Balletta L, Karginova O, Jordan J, Combest A, Bridges A, Prat A, Cheang MC, Herschkowitz JI, Rosen JM, Zamboni W, Sharpless NE, Perou CM. Usary J, et al. Among authors: roberts pj. Clin Cancer Res. 2013 Sep 1;19(17):4889-99. doi: 10.1158/1078-0432.CCR-13-0522. Epub 2013 Jun 18. Clin Cancer Res. 2013. PMID: 23780888 Free PMC article.
Alterations of LKB1 and KRAS and risk of brain metastasis: comprehensive characterization by mutation analysis, copy number, and gene expression in non-small-cell lung carcinoma.
Zhao N, Wilkerson MD, Shah U, Yin X, Wang A, Hayward MC, Roberts P, Lee CB, Parsons AM, Thorne LB, Haithcock BE, Grilley-Olson JE, Stinchcombe TE, Funkhouser WK, Wong KK, Sharpless NE, Hayes DN. Zhao N, et al. Lung Cancer. 2014 Nov;86(2):255-61. doi: 10.1016/j.lungcan.2014.08.013. Epub 2014 Aug 30. Lung Cancer. 2014. PMID: 25224251 Free PMC article.
Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy.
Roberts PJ, Bisi JE, Strum JC, Combest AJ, Darr DB, Usary JE, Zamboni WC, Wong KK, Perou CM, Sharpless NE. Roberts PJ, et al. J Natl Cancer Inst. 2012 Mar 21;104(6):476-87. doi: 10.1093/jnci/djs002. Epub 2012 Feb 1. J Natl Cancer Inst. 2012. PMID: 22302033 Free PMC article.
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Chen Z, Cheng K, Walton Z, Wang Y, Ebi H, Shimamura T, Liu Y, Tupper T, Ouyang J, Li J, Gao P, Woo MS, Xu C, Yanagita M, Altabef A, Wang S, Lee C, Nakada Y, Peña CG, Sun Y, Franchetti Y, Yao C, Saur A, Cameron MD, Nishino M, Hayes DN, Wilkerson MD, Roberts PJ, Lee CB, Bardeesy N, Butaney M, Chirieac LR, Costa DB, Jackman D, Sharpless NE, Castrillon DH, Demetri GD, Jänne PA, Pandolfi PP, Cantley LC, Kung AL, Engelman JA, Wong KK. Chen Z, et al. Among authors: roberts pj. Nature. 2012 Mar 18;483(7391):613-7. doi: 10.1038/nature10937. Nature. 2012. PMID: 22425996 Free PMC article.
CDK4/6 inhibition enhances antitumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCLC receiving chemotherapy.
Lai AY, Sorrentino JA, Dragnev KH, Weiss JM, Owonikoko TK, Rytlewski JA, Hood J, Yang Z, Malik RK, Strum JC, Roberts PJ. Lai AY, et al. Among authors: roberts pj. J Immunother Cancer. 2020 Oct;8(2):e000847. doi: 10.1136/jitc-2020-000847. J Immunother Cancer. 2020. PMID: 33004541 Free PMC article.
359 results