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Identification of orally available naphthyridine protein kinase D inhibitors.
J Med Chem. 2010 Aug 12;53(15):5400-21. doi: 10.1021/jm100075z.
J Med Chem. 2010.
PMID: 20684591
2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes.
van Eis MJ, Evenou JP, Floersheim P, Gaul C, Cowan-Jacob SW, Monovich L, Rummel G, Schuler W, Stark W, Strauss A, von Matt A, Vangrevelinghe E, Wagner J, Soldermann N.
van Eis MJ, et al. Among authors: von matt a.
Bioorg Med Chem Lett. 2011 Dec 15;21(24):7367-72. doi: 10.1016/j.bmcl.2011.10.025. Epub 2011 Oct 21.
Bioorg Med Chem Lett. 2011.
PMID: 22078216
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New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck.
Gommermann N, Buehlmayer P, von Matt A, Breitenstein W, Masuya K, Pirard B, Furet P, Cowan-Jacob SW, Weckbecker G.
Gommermann N, et al. Among authors: von matt a.
Bioorg Med Chem Lett. 2010 Jun 15;20(12):3628-31. doi: 10.1016/j.bmcl.2010.04.112. Epub 2010 Apr 29.
Bioorg Med Chem Lett. 2010.
PMID: 20483608
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Aromatic quinolinecarboxamides as selective, orally active antibody production inhibitors for prevention of acute xenograft rejection.
Papageorgiou C, von Matt A, Joergensen J, Andersen E, Wagner K, Beerli C, Than T, Borer X, Florineth A, Rihs G, Schreier MH, Weckbecker G, Heusser C.
Papageorgiou C, et al. Among authors: von matt a.
J Med Chem. 2001 Jun 7;44(12):1986-92. doi: 10.1021/jm010822m.
J Med Chem. 2001.
PMID: 11384243
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Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.
Hoegenauer K, Soldermann N, Hebach C, Hollingworth GJ, Lewis I, von Matt A, Smith AB, Wolf RM, Wilcken R, Haasen D, Burkhart C, Zécri F.
Hoegenauer K, et al. Among authors: von matt a.
Bioorg Med Chem Lett. 2016 Dec 1;26(23):5657-5662. doi: 10.1016/j.bmcl.2016.10.069. Epub 2016 Oct 27.
Bioorg Med Chem Lett. 2016.
PMID: 27816514
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Selective boron-containing thrombin inhibitors--X-ray analysis reveals surprising binding mode.
von Matt A, Ehrhardt C, Burkhard P, Metternich R, Walkinshaw M, Tapparelli C.
von Matt A, et al.
Bioorg Med Chem. 2000 Sep;8(9):2291-303. doi: 10.1016/s0968-0896(00)00147-4.
Bioorg Med Chem. 2000.
PMID: 11026541
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