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Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.
Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium; Morris AP, Meyer CG, Horstmann RD, Hill AVS. Thye T, et al. Among authors: hill pc, hill avs. Nat Genet. 2010 Sep;42(9):739-741. doi: 10.1038/ng.639. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694014 Free PMC article.
Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.
Tosh K, Campbell SJ, Fielding K, Sillah J, Bah B, Gustafson P, Manneh K, Lisse I, Sirugo G, Bennett S, Aaby P, McAdam KPWJ, Bah-Sow O, Lienhardt C, Kramnik I, Hill AVS. Tosh K, et al. Among authors: hill avs. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10364-10368. doi: 10.1073/pnas.0603340103. Epub 2006 Jun 27. Proc Natl Acad Sci U S A. 2006. PMID: 16803959 Free PMC article.
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.
Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV. Khor CC, et al. Nat Genet. 2007 Apr;39(4):523-8. doi: 10.1038/ng1976. Epub 2007 Feb 25. Nat Genet. 2007. PMID: 17322885 Free PMC article.
461 results