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Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.
Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium; Morris AP, Meyer CG, Horstmann RD, Hill AVS. Thye T, et al. Among authors: osei i. Nat Genet. 2010 Sep;42(9):739-741. doi: 10.1038/ng.639. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694014 Free PMC article.
ALOX5 variants associated with susceptibility to human pulmonary tuberculosis.
Herb F, Thye T, Niemann S, Browne EN, Chinbuah MA, Gyapong J, Osei I, Owusu-Dabo E, Werz O, Rüsch-Gerdes S, Horstmann RD, Meyer CG. Herb F, et al. Among authors: osei i. Hum Mol Genet. 2008 Apr 1;17(7):1052-60. doi: 10.1093/hmg/ddm378. Epub 2008 Jan 3. Hum Mol Genet. 2008. PMID: 18174194
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains.
Intemann CD, Thye T, Niemann S, Browne EN, Amanua Chinbuah M, Enimil A, Gyapong J, Osei I, Owusu-Dabo E, Helm S, Rüsch-Gerdes S, Horstmann RD, Meyer CG. Intemann CD, et al. Among authors: osei i. PLoS Pathog. 2009 Sep;5(9):e1000577. doi: 10.1371/journal.ppat.1000577. Epub 2009 Sep 11. PLoS Pathog. 2009. PMID: 19750224 Free PMC article.
A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.
Möller M, Flachsbart F, Till A, Thye T, Horstmann RD, Meyer CG, Osei I, van Helden PD, Hoal EG, Schreiber S, Nebel A, Franke A. Möller M, et al. Among authors: osei i. Am J Respir Crit Care Med. 2010 Feb 15;181(4):388-93. doi: 10.1164/rccm.200905-0678OC. Epub 2009 Dec 10. Am J Respir Crit Care Med. 2010. PMID: 20007930 Free PMC article.
Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis.
Thye T, Niemann S, Walter K, Homolka S, Intemann CD, Chinbuah MA, Enimil A, Gyapong J, Osei I, Owusu-Dabo E, Rüsch-Gerdes S, Horstmann RD, Ehlers S, Meyer CG. Thye T, et al. Among authors: osei i. PLoS One. 2011;6(6):e20908. doi: 10.1371/journal.pone.0020908. Epub 2011 Jun 10. PLoS One. 2011. PMID: 21695215 Free PMC article.
No associations of human pulmonary tuberculosis with Sp110 variants.
Thye T, Browne EN, Chinbuah MA, Gyapong J, Osei I, Owusu-Dabo E, Niemann S, Rüsch-Gerdes S, Horstmann RD, Meyer CG. Thye T, et al. Among authors: osei i. J Med Genet. 2006 Jul;43(7):e32. doi: 10.1136/jmg.2005.037960. J Med Genet. 2006. PMID: 16816019 Free PMC article.
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