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Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
Ashton GH, Morton JP, Myant K, Phesse TJ, Ridgway RA, Marsh V, Wilkins JA, Athineos D, Muncan V, Kemp R, Neufeld K, Clevers H, Brunton V, Winton DJ, Wang X, Sears RC, Clarke AR, Frame MC, Sansom OJ. Ashton GH, et al. Among authors: kemp r. Dev Cell. 2010 Aug 17;19(2):259-69. doi: 10.1016/j.devcel.2010.07.015. Dev Cell. 2010. PMID: 20708588 Free PMC article.
Defining stem cell dynamics in models of intestinal tumor initiation.
Vermeulen L, Morrissey E, van der Heijden M, Nicholson AM, Sottoriva A, Buczacki S, Kemp R, Tavaré S, Winton DJ. Vermeulen L, et al. Among authors: kemp r. Science. 2013 Nov 22;342(6161):995-8. doi: 10.1126/science.1243148. Science. 2013. PMID: 24264992
Bcl-2 is a critical mediator of intestinal transformation.
van der Heijden M, Zimberlin CD, Nicholson AM, Colak S, Kemp R, Meijer SL, Medema JP, Greten FR, Jansen M, Winton DJ, Vermeulen L. van der Heijden M, et al. Among authors: kemp r. Nat Commun. 2016 Mar 9;7:10916. doi: 10.1038/ncomms10916. Nat Commun. 2016. PMID: 26956214 Free PMC article.
Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.
Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Göttgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A. Azzarelli R, et al. Among authors: kemp r. Dev Cell. 2017 May 8;41(3):274-286.e5. doi: 10.1016/j.devcel.2017.04.004. Epub 2017 Apr 27. Dev Cell. 2017. PMID: 28457793 Free PMC article.
713 results