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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.
Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, Boni J, Maicas M, Du S, Iorio F, Herranz-Ors C, Islam A, Prado X, Llorente A, Petit A, Vidal A, Català I, Soler T, Venturas G, Rojo-Sebastian A, Serra H, Cuadras D, Blanco I, Lozano J, Canals F, Sieuwerts AM, de Weerd V, Look MP, Puertas S, García N, Perkins AS, Bonifaci N, Skowron M, Gómez-Baldó L, Hernández V, Martínez-Aranda A, Martínez-Iniesta M, Serrat X, Cerón J, Brunet J, Barretina MP, Gil M, Falo C, Fernández A, Morilla I, Pernas S, Plà MJ, Andreu X, Seguí MA, Ballester R, Castellà E, Nellist M, Morales S, Valls J, Velasco A, Matias-Guiu X, Figueras A, Sánchez-Mut JV, Sánchez-Céspedes M, Cordero A, Gómez-Miragaya J, Palomero L, Gómez A, Gajewski TF, Cohen EEW, Jesiotr M, Bodnar L, Quintela-Fandino M, López-Bigas N, Valdés-Mas R, Puente XS, Viñals F, Casanovas O, Graupera M, Hernández-Losa J, Ramón Y Cajal S, García-Alonso L, Saez-Rodriguez J, Esteller M, Sierra A, Martín-Martín N, Matheu A, Carracedo A, González-Suárez E, Nanjundan M, Cortés J, Lázaro C, Odero MD, Martens JWM, Moreno-Bueno G, Barcellos-Hoff MH, Villanueva A, Gomis RR, Pujana MA. Mateo F, et al. Among authors: islam a. Oncogene. 2017 May 11;36(19):2737-2749. doi: 10.1038/onc.2016.427. Epub 2016 Dec 19. Oncogene. 2017. PMID: 27991928 Free PMC article.
The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma.
Barneda-Zahonero B, Collazo O, Azagra A, Fernández-Duran I, Serra-Musach J, Islam AB, Vega-García N, Malatesta R, Camós M, Gómez A, Román-González L, Vidal A, López-Bigas N, Villanueva A, Esteller M, Parra M. Barneda-Zahonero B, et al. Among authors: islam ab. Cell Death Dis. 2015 Feb 12;6(2):e1635. doi: 10.1038/cddis.2014.594. Cell Death Dis. 2015. PMID: 25675295 Free PMC article.
An intronic microRNA links Rb/E2F and EGFR signaling.
Truscott M, Islam AB, Lightfoot J, López-Bigas N, Frolov MV. Truscott M, et al. PLoS Genet. 2014 Jul 24;10(7):e1004493. doi: 10.1371/journal.pgen.1004493. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25058496 Free PMC article.
Selective targeting of histone methylation.
Islam AB, Richter WF, Lopez-Bigas N, Benevolenskaya EV. Islam AB, et al. Cell Cycle. 2011 Feb 1;10(3):413-24. doi: 10.4161/cc.10.3.14705. Epub 2011 Feb 1. Cell Cycle. 2011. PMID: 21270517 Free PMC article.
NF-κB directly mediates epigenetic deregulation of common microRNAs in Epstein-Barr virus-mediated transformation of B-cells and in lymphomas.
Vento-Tormo R, Rodríguez-Ubreva J, Lisio LD, Islam AB, Urquiza JM, Hernando H, López-Bigas N, Shannon-Lowe C, Martínez N, Montes-Moreno S, Piris MA, Ballestar E. Vento-Tormo R, et al. Among authors: islam ab. Nucleic Acids Res. 2014;42(17):11025-39. doi: 10.1093/nar/gku826. Epub 2014 Sep 8. Nucleic Acids Res. 2014. PMID: 25200074 Free PMC article.
2,177 results