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Combined iron chelation therapy.
Galanello R, Agus A, Campus S, Danjou F, Giardina PJ, Grady RW. Galanello R, et al. Among authors: grady rw. Ann N Y Acad Sci. 2010 Aug;1202:79-86. doi: 10.1111/j.1749-6632.2010.05591.x. Ann N Y Acad Sci. 2010. PMID: 20712777
Increased survival and reversion of iron-induced cardiac disease in patients with thalassemia major receiving intensive combined chelation therapy as compared to desferoxamine alone.
Lai ME, Grady RW, Vacquer S, Pepe A, Carta MP, Bina P, Sau F, Cianciulli P, Maggio A, Galanello R, Farci P. Lai ME, et al. Among authors: grady rw. Blood Cells Mol Dis. 2010 Aug 15;45(2):136-9. doi: 10.1016/j.bcmd.2010.05.005. Epub 2010 Jun 17. Blood Cells Mol Dis. 2010. PMID: 20678715
Hepcidin and Hfe in iron overload in beta-thalassemia.
Gardenghi S, Ramos P, Follenzi A, Rao N, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: grady rw. Ann N Y Acad Sci. 2010 Aug;1202:221-5. doi: 10.1111/j.1749-6632.2010.05595.x. Ann N Y Acad Sci. 2010. PMID: 20712796 Free PMC article. Review.
Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.
Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P; Thalassemia Clinical Research Network. Walter PB, et al. Haematologica. 2008 Jun;93(6):817-25. doi: 10.3324/haematol.11755. Epub 2008 May 10. Haematologica. 2008. PMID: 18469351 Free article. Clinical Trial.
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.
Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: grady rw. J Clin Invest. 2010 Dec;120(12):4466-77. doi: 10.1172/JCI41717. Epub 2010 Nov 22. J Clin Invest. 2010. PMID: 21099112 Free PMC article.
Increased leucocyte apoptosis in transfused β-thalassaemia patients.
Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P; Thalassemia Clinical Research Network. Walter PB, et al. Among authors: grady rw. Br J Haematol. 2013 Feb;160(3):399-403. doi: 10.1111/bjh.12076. Epub 2012 Dec 6. Br J Haematol. 2013. PMID: 23216540 Free PMC article.
Bone loss caused by iron overload in a murine model: importance of oxidative stress.
Tsay J, Yang Z, Ross FP, Cunningham-Rundles S, Lin H, Coleman R, Mayer-Kuckuk P, Doty SB, Grady RW, Giardina PJ, Boskey AL, Vogiatzi MG. Tsay J, et al. Among authors: grady rw. Blood. 2010 Oct 7;116(14):2582-9. doi: 10.1182/blood-2009-12-260083. Epub 2010 Jun 16. Blood. 2010. PMID: 20554970 Free PMC article.
152 results