Kumar S - Search Results

1

Metabolism and excretion of [14C]taranabant, a cannabinoid-1 inverse agonist, in humans.

Karanam B, Addy C, Bateman T, Reddy VB, Li S, Dean D, Li H, Jones A, Schenk D, Zhang AS, Braun M, Freeman A, Flach S, Stoch A, Chodakewitz J, Wagner JA, Kumar S. Karanam B, et al. Among authors: kumar s. Xenobiotica. 2010 Oct;40(10):691-700. doi: 10.3109/00498254.2010.509820. Xenobiotica. 2010. PMID: 20722472

2

In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys.

Reddy VB, Doss GA, Karanam BV, Samuel K, Lanza TJ Jr, Lin LS, Yu NX, Zhang AS, Raab CE, Stearns RA, Kumar S. Reddy VB, et al. Among authors: kumar s. Xenobiotica. 2010 Sep;40(9):650-62. doi: 10.3109/00498254.2010.501117. Xenobiotica. 2010. PMID: 20608842

3

Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans.

Kumar S, Tan EY, Hartmann G, Biddle Z, Bergman AJ, Dru J, Ho JZ, Jones AN, Staskiewicz SJ, Braun MP, Karanam B, Dean DC, Gendrano IN, Graves MW, Wagner JA, Krishna R. Kumar S, et al. Drug Metab Dispos. 2010 Mar;38(3):474-83. doi: 10.1124/dmd.109.028704. Epub 2009 Dec 16. Drug Metab Dispos. 2010. PMID: 20016053 Clinical Trial.

4

Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys.

Tan EY, Hartmann G, Chen Q, Pereira A, Bradley S, Doss G, Zhang AS, Ho JZ, Braun MP, Dean DC, Tang W, Kumar S. Tan EY, et al. Among authors: kumar s. Drug Metab Dispos. 2010 Mar;38(3):459-73. doi: 10.1124/dmd.109.028696. Epub 2009 Dec 16. Drug Metab Dispos. 2010. PMID: 20016052

5

Glutathione S-transferase catalyzed desulfonylation of a sulfonylfuropyridine.

Bateman TJ, Debenham JS, Madsen-Duggan C, Toupence RB, Walsh TF, Truong Q, Bradley SA, Doss GA, Kumar S, Reddy VB. Bateman TJ, et al. Among authors: kumar s. Drug Metab Dispos. 2010 Jan;38(1):108-14. doi: 10.1124/dmd.109.029801. Drug Metab Dispos. 2010. PMID: 19797605

6

Lymphatic absorption, metabolism, and excretion of a therapeutic peptide in dogs and rats.

Zou Y, Bateman TJ, Adreani C, Shen X, Cunningham PK, Wang B, Trinh T, Christine A, Hong X, Nunes CN, Johnson CV, Zhang AS, Staskiewicz SJ, Braun M, Kumar S, Reddy VB. Zou Y, et al. Among authors: kumar s. Drug Metab Dispos. 2013 Dec;41(12):2206-14. doi: 10.1124/dmd.113.051524. Epub 2013 Oct 2. Drug Metab Dispos. 2013. PMID: 24088325

7

Application of chimeric mice with humanized liver for study of human-specific drug metabolism.

Bateman TJ, Reddy VG, Kakuni M, Morikawa Y, Kumar S. Bateman TJ, et al. Among authors: kumar s. Drug Metab Dispos. 2014 Jun;42(6):1055-65. doi: 10.1124/dmd.114.056978. Epub 2014 Apr 3. Drug Metab Dispos. 2014. PMID: 24700822

8

Absorption, metabolism and excretion of [¹⁴C]omarigliptin, a once-weekly DPP-4 inhibitor, in humans.

Xu S, Tatosian D, Mcintosh I, Caceres M, Matthews C, Samuel K, Selverian D, Kumar S, Kauh E. Xu S, et al. Among authors: kumar s. Xenobiotica. 2018 Jun;48(6):584-591. doi: 10.1080/00498254.2017.1346333. Epub 2017 Jul 25. Xenobiotica. 2018. PMID: 28665228 Clinical Trial.

9

Furo[2,3-b]pyridine-based cannabinoid-1 receptor inverse agonists: synthesis and biological evaluation. Part 1.

Debenham JS, Madsen-Duggan CB, Toupence RB, Walsh TF, Wang J, Tong X, Kumar S, Lao J, Fong TM, Xiao JC, Huang CR, Shen CP, Feng Y, Marsh DJ, Stribling DS, Shearman LP, Strack AM, Goulet MT. Debenham JS, et al. Among authors: kumar s. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1448-52. doi: 10.1016/j.bmcl.2009.12.065. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20096577

10

Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma.

Hop CE, Wang Y, Kumar S, Elipe MV, Raab CE, Dean DC, Poon GK, Keohane CA, Strauss J, Chiu SH, Curtis N, Elliott J, Gerhard U, Locker K, Morrison D, Mortishire-Smith R, Thomas S, Watt AP, Evans DC. Hop CE, et al. Among authors: kumar s. Drug Metab Dispos. 2002 Aug;30(8):937-43. doi: 10.1124/dmd.30.8.937. Drug Metab Dispos. 2002. PMID: 12124313

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