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Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans.
Dao DT, Mahon PB, Cai X, Kovacsics CE, Blackwell RA, Arad M, Shi J, Zandi PP, O'Donnell P; Bipolar Genome Study (BiGS) Consortium; Knowles JA, Weissman MM, Coryell W, Scheftner WA, Lawson WB, Levinson DF, Thompson SM, Potash JB, Gould TD. Dao DT, et al. Among authors: cai x. Biol Psychiatry. 2010 Nov 1;68(9):801-10. doi: 10.1016/j.biopsych.2010.06.019. Epub 2010 Aug 17. Biol Psychiatry. 2010. PMID: 20723887 Free PMC article.
An excitatory synapse hypothesis of depression.
Thompson SM, Kallarackal AJ, Kvarta MD, Van Dyke AM, LeGates TA, Cai X. Thompson SM, et al. Among authors: cai x. Trends Neurosci. 2015 May;38(5):279-94. doi: 10.1016/j.tins.2015.03.003. Epub 2015 Apr 14. Trends Neurosci. 2015. PMID: 25887240 Free PMC article. Review.
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