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A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.
Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Timmermann B, et al. Among authors: kruger a. Aging (Albany NY). 2010 Aug;2(8):475-86. doi: 10.18632/aging.100187. Aging (Albany NY). 2010. PMID: 20729566 Free PMC article.
The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmanesfahar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M. Alam MT, et al. Among authors: kruger a. Nat Microbiol. 2016 Feb 1;1:15030. doi: 10.1038/nmicrobiol.2015.30. Nat Microbiol. 2016. PMID: 27572163 Free PMC article.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Segal J, Mülleder M, Krüger A, Adler T, Scholze-Wittler M, Becker L, Calzada-Wack J, Garrett L, Hölter SM, Rathkolb B, Rozman J, Racz I, Fischer R, Busch DH, Neff F, Klingenspor M, Klopstock T, Grüning NM, Michel S, Lukaszewska-McGreal B, Voigt I, Hartmann L, Timmermann B, Lehrach H, Wolf E, Wurst W, Gailus-Durner V, Fuchs H, H de Angelis M, Schrewe H, Yuneva M, Ralser M. Segal J, et al. Among authors: kruger a. J Inherit Metab Dis. 2019 Sep;42(5):839-849. doi: 10.1002/jimd.12105. Epub 2019 Jun 11. J Inherit Metab Dis. 2019. PMID: 31111503 Free PMC article.
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway.
Stincone A, Prigione A, Cramer T, Wamelink MM, Campbell K, Cheung E, Olin-Sandoval V, Grüning NM, Krüger A, Tauqeer Alam M, Keller MA, Breitenbach M, Brindle KM, Rabinowitz JD, Ralser M. Stincone A, et al. Among authors: kruger a. Biol Rev Camb Philos Soc. 2015 Aug;90(3):927-63. doi: 10.1111/brv.12140. Epub 2014 Sep 22. Biol Rev Camb Philos Soc. 2015. PMID: 25243985 Free PMC article. Review.
1,114 results