McCarthy A - Search Results

1

A marker of homologous recombination predicts pathologic complete response to neoadjuvant chemotherapy in primary breast cancer.

Graeser M, McCarthy A, Lord CJ, Savage K, Hills M, Salter J, Orr N, Parton M, Smith IE, Reis-Filho JS, Dowsett M, Ashworth A, Turner NC. Graeser M, et al. Among authors: mccarthy a. Clin Cancer Res. 2010 Dec 15;16(24):6159-68. doi: 10.1158/1078-0432.CCR-10-1027. Epub 2010 Aug 27. Clin Cancer Res. 2010. PMID: 20802015 Free PMC article.

2

A mouse model of basal-like breast carcinoma with metaplastic elements.

McCarthy A, Savage K, Gabriel A, Naceur C, Reis-Filho JS, Ashworth A. McCarthy A, et al. J Pathol. 2007 Mar;211(4):389-98. doi: 10.1002/path.2124. J Pathol. 2007. PMID: 17212342

3

Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.

McCarthy A, Lord CJ, Savage K, Grigoriadis A, Smith DP, Weigelt B, Reis-Filho JS, Ashworth A. McCarthy A, et al. J Pathol. 2009 Nov;219(3):306-16. doi: 10.1002/path.2599. J Pathol. 2009. PMID: 19681070

4

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.

Mendes-Pereira AM, Martin SA, Brough R, McCarthy A, Taylor JR, Kim JS, Waldman T, Lord CJ, Ashworth A. Mendes-Pereira AM, et al. Among authors: mccarthy a. EMBO Mol Med. 2009 Sep;1(6-7):315-22. doi: 10.1002/emmm.200900041. EMBO Mol Med. 2009. PMID: 20049735 Free PMC article.

5

Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition.

Sourisseau T, Maniotis D, McCarthy A, Tang C, Lord CJ, Ashworth A, Linardopoulos S. Sourisseau T, et al. Among authors: mccarthy a. EMBO Mol Med. 2010 Apr;2(4):130-42. doi: 10.1002/emmm.201000068. EMBO Mol Med. 2010. PMID: 20373286 Free PMC article.

6

Lkb1 deficiency causes prostate neoplasia in the mouse.

Pearson HB, McCarthy A, Collins CM, Ashworth A, Clarke AR. Pearson HB, et al. Among authors: mccarthy a. Cancer Res. 2008 Apr 1;68(7):2223-32. doi: 10.1158/0008-5472.CAN-07-5169. Cancer Res. 2008. PMID: 18381428 Free article.

7

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.

Martin SA, McCarthy A, Barber LJ, Burgess DJ, Parry S, Lord CJ, Ashworth A. Martin SA, et al. Among authors: mccarthy a. EMBO Mol Med. 2009 Sep;1(6-7):323-37. doi: 10.1002/emmm.200900040. EMBO Mol Med. 2009. PMID: 20049736 Free PMC article.

8

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells.

Molyneux G, Geyer FC, Magnay FA, McCarthy A, Kendrick H, Natrajan R, Mackay A, Grigoriadis A, Tutt A, Ashworth A, Reis-Filho JS, Smalley MJ. Molyneux G, et al. Among authors: mccarthy a. Cell Stem Cell. 2010 Sep 3;7(3):403-17. doi: 10.1016/j.stem.2010.07.010. Cell Stem Cell. 2010. PMID: 20804975 Free article.

9

Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification.

Howard B, Panchal H, McCarthy A, Ashworth A. Howard B, et al. Among authors: mccarthy a. Genes Dev. 2005 Sep 1;19(17):2078-90. doi: 10.1101/gad.338505. Genes Dev. 2005. PMID: 16140987 Free PMC article.

10

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.

Francis JC, McCarthy A, Thomsen MK, Ashworth A, Swain A. Francis JC, et al. Among authors: mccarthy a. PLoS Genet. 2010 Jun 24;6(6):e1000995. doi: 10.1371/journal.pgen.1000995. PLoS Genet. 2010. PMID: 20585617 Free PMC article.

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