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525 results

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Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial.
Matucci-Cerinic M, Denton CP, Furst DE, Mayes MD, Hsu VM, Carpentier P, Wigley FM, Black CM, Fessler BJ, Merkel PA, Pope JE, Sweiss NJ, Doyle MK, Hellmich B, Medsger TA Jr, Morganti A, Kramer F, Korn JH, Seibold JR. Matucci-Cerinic M, et al. Among authors: denton cp. Ann Rheum Dis. 2011 Jan;70(1):32-8. doi: 10.1136/ard.2010.130658. Epub 2010 Aug 30. Ann Rheum Dis. 2011. PMID: 20805294 Free PMC article. Clinical Trial.
Pulmonary hypertension in systemic sclerosis.
Denton CP, Black CM. Denton CP, et al. Rheum Dis Clin North Am. 2003 May;29(2):335-49, vii. doi: 10.1016/s0889-857x(03)00024-3. Rheum Dis Clin North Am. 2003. PMID: 12841298 Review.
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.
Shi-Wen X, Chen Y, Denton CP, Eastwood M, Renzoni EA, Bou-Gharios G, Pearson JD, Dashwood M, du Bois RM, Black CM, Leask A, Abraham DJ. Shi-Wen X, et al. Among authors: denton cp. Mol Biol Cell. 2004 Jun;15(6):2707-19. doi: 10.1091/mbc.e03-12-0902. Epub 2004 Mar 26. Mol Biol Cell. 2004. PMID: 15047866 Free PMC article.
Scleroderma--clinical and pathological advances.
Denton CP, Black CM. Denton CP, et al. Best Pract Res Clin Rheumatol. 2004 Jun;18(3):271-90. doi: 10.1016/j.berh.2004.03.001. Best Pract Res Clin Rheumatol. 2004. PMID: 15158741 Review.
Targeted therapy comes of age in scleroderma.
Denton CP, Black CM. Denton CP, et al. Trends Immunol. 2005 Nov;26(11):596-602. doi: 10.1016/j.it.2005.09.002. Epub 2005 Sep 15. Trends Immunol. 2005. PMID: 16168710 Review.
A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.
Hoyles RK, Ellis RW, Wellsbury J, Lees B, Newlands P, Goh NS, Roberts C, Desai S, Herrick AL, McHugh NJ, Foley NM, Pearson SB, Emery P, Veale DJ, Denton CP, Wells AU, Black CM, du Bois RM. Hoyles RK, et al. Among authors: denton cp. Arthritis Rheum. 2006 Dec;54(12):3962-70. doi: 10.1002/art.22204. Arthritis Rheum. 2006. PMID: 17133610 Free article. Clinical Trial.
Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: a multicenter, randomized, placebo-controlled phase I/II trial of CAT-192.
Denton CP, Merkel PA, Furst DE, Khanna D, Emery P, Hsu VM, Silliman N, Streisand J, Powell J, Akesson A, Coppock J, Hoogen Fv, Herrick A, Mayes MD, Veale D, Haas J, Ledbetter S, Korn JH, Black CM, Seibold JR; Cat-192 Study Group; Scleroderma Clinical Trials Consortium. Denton CP, et al. Arthritis Rheum. 2007 Jan;56(1):323-33. doi: 10.1002/art.22289. Arthritis Rheum. 2007. PMID: 17195236 Free article. Clinical Trial.
525 results