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Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Highfill SL, Rodriguez PC, Zhou Q, Goetz CA, Koehn BH, Veenstra R, Taylor PA, Panoskaltsis-Mortari A, Serody JS, Munn DH, Tolar J, Ochoa AC, Blazar BR. Highfill SL, et al. Among authors: ochoa ac. Blood. 2010 Dec 16;116(25):5738-47. doi: 10.1182/blood-2010-06-287839. Epub 2010 Aug 31. Blood. 2010. PMID: 20807889 Free PMC article.
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
Rodriguez PC, Hernandez CP, Quiceno D, Dubinett SM, Zabaleta J, Ochoa JB, Gilbert J, Ochoa AC. Rodriguez PC, et al. Among authors: ochoa ac, ochoa jb. J Exp Med. 2005 Oct 3;202(7):931-9. doi: 10.1084/jem.20050715. Epub 2005 Sep 26. J Exp Med. 2005. PMID: 16186186 Free PMC article.
136 results