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Insight into the molecular mechanism of the multitasking kinesin-8 motor.
Peters C, Brejc K, Belmont L, Bodey AJ, Lee Y, Yu M, Guo J, Sakowicz R, Hartman J, Moores CA. Peters C, et al. Among authors: sakowicz r. EMBO J. 2010 Oct 20;29(20):3437-47. doi: 10.1038/emboj.2010.220. Epub 2010 Sep 3. EMBO J. 2010. PMID: 20818331 Free PMC article.
A mechanism for microtubule depolymerization by KinI kinesins.
Moores CA, Yu M, Guo J, Beraud C, Sakowicz R, Milligan RA. Moores CA, et al. Among authors: sakowicz r. Mol Cell. 2002 Apr;9(4):903-9. doi: 10.1016/s1097-2765(02)00503-8. Mol Cell. 2002. PMID: 11983180 Free article.
Structure of a kinesin microtubule depolymerization machine.
Shipley K, Hekmat-Nejad M, Turner J, Moores C, Anderson R, Milligan R, Sakowicz R, Fletterick R. Shipley K, et al. Among authors: sakowicz r. EMBO J. 2004 Apr 7;23(7):1422-32. doi: 10.1038/sj.emboj.7600165. Epub 2004 Mar 18. EMBO J. 2004. PMID: 15029249 Free PMC article.
Mechanism of inhibition of human KSP by ispinesib.
Lad L, Luo L, Carson JD, Wood KW, Hartman JJ, Copeland RA, Sakowicz R. Lad L, et al. Among authors: sakowicz r. Biochemistry. 2008 Mar 18;47(11):3576-85. doi: 10.1021/bi702061g. Epub 2008 Feb 22. Biochemistry. 2008. PMID: 18290633
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E.
Wood KW, Lad L, Luo L, Qian X, Knight SD, Nevins N, Brejc K, Sutton D, Gilmartin AG, Chua PR, Desai R, Schauer SP, McNulty DE, Annan RS, Belmont LD, Garcia C, Lee Y, Diamond MA, Faucette LF, Giardiniere M, Zhang S, Sun CM, Vidal JD, Lichtsteiner S, Cornwell WD, Greshock JD, Wooster RF, Finer JT, Copeland RA, Huang PS, Morgans DJ Jr, Dhanak D, Bergnes G, Sakowicz R, Jackson JR. Wood KW, et al. Among authors: sakowicz r. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5839-44. doi: 10.1073/pnas.0915068107. Epub 2010 Feb 18. Proc Natl Acad Sci U S A. 2010. PMID: 20167803 Free PMC article.
Cardiac myosin activation: a potential therapeutic approach for systolic heart failure.
Malik FI, Hartman JJ, Elias KA, Morgan BP, Rodriguez H, Brejc K, Anderson RL, Sueoka SH, Lee KH, Finer JT, Sakowicz R, Baliga R, Cox DR, Garard M, Godinez G, Kawas R, Kraynack E, Lenzi D, Lu PP, Muci A, Niu C, Qian X, Pierce DW, Pokrovskii M, Suehiro I, Sylvester S, Tochimoto T, Valdez C, Wang W, Katori T, Kass DA, Shen YT, Vatner SF, Morgans DJ. Malik FI, et al. Among authors: sakowicz r. Science. 2011 Mar 18;331(6023):1439-43. doi: 10.1126/science.1200113. Science. 2011. PMID: 21415352 Free PMC article.
50 results