Liénard BM - Search Results

1

Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.

Conejo-Garcia A, McDonough MA, Loenarz C, McNeill LA, Hewitson KS, Ge W, Liénard BM, Schofield CJ, Clifton IJ. Conejo-Garcia A, et al. Among authors: lienard bm. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6125-8. doi: 10.1016/j.bmcl.2010.08.032. Epub 2010 Aug 10. Bioorg Med Chem Lett. 2010. PMID: 20822901

2

Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases.

Lienard BM, Conejo-García A, Stolze I, Loenarz C, Oldham NJ, Ratcliffe PJ, Schofield CJ. Lienard BM, et al. Chem Commun (Camb). 2008 Dec 21;(47):6393-5. doi: 10.1039/b814440k. Epub 2008 Nov 5. Chem Commun (Camb). 2008. PMID: 19048166

3

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

Stubbs CJ, Loenarz C, Mecinović J, Yeoh KK, Hindley N, Liénard BM, Sobott F, Schofield CJ, Flashman E. Stubbs CJ, et al. Among authors: lienard bm. J Med Chem. 2009 May 14;52(9):2799-805. doi: 10.1021/jm900285r. J Med Chem. 2009. PMID: 19364117

4

Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates.

Hewitson KS, Liénard BM, McDonough MA, Clifton IJ, Butler D, Soares AS, Oldham NJ, McNeill LA, Schofield CJ. Hewitson KS, et al. Among authors: lienard bm. J Biol Chem. 2007 Feb 2;282(5):3293-301. doi: 10.1074/jbc.M608337200. Epub 2006 Nov 29. J Biol Chem. 2007. PMID: 17135241 Free article.

5

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.

Rose NR, Ng SS, Mecinović J, Liénard BM, Bello SH, Sun Z, McDonough MA, Oppermann U, Schofield CJ. Rose NR, et al. Among authors: lienard bm. J Med Chem. 2008 Nov 27;51(22):7053-6. doi: 10.1021/jm800936s. J Med Chem. 2008. PMID: 18942826

6

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).

McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ. McDonough MA, et al. Among authors: lienard bm. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. doi: 10.1073/pnas.0601283103. Epub 2006 Jun 16. Proc Natl Acad Sci U S A. 2006. PMID: 16782814 Free PMC article.

7

Inhibitors of the FEZ-1 metallo-beta-lactamase.

Liénard BM, Horsfall LE, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):964-8. doi: 10.1016/j.bmcl.2006.11.053. Epub 2006 Nov 18. Bioorg Med Chem Lett. 2007. PMID: 17157014

8

Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.

Liénard BM, Hüting R, Lassaux P, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. J Med Chem. 2008 Feb 14;51(3):684-8. doi: 10.1021/jm070866g. Epub 2008 Jan 19. J Med Chem. 2008. PMID: 18205296

9

Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors.

Liénard BM, Selevsek N, Oldham NJ, Schofield CJ. Liénard BM, et al. ChemMedChem. 2007 Feb;2(2):175-9. doi: 10.1002/cmdc.200600250. ChemMedChem. 2007. PMID: 17206734 No abstract available.

10

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U. Ng SS, et al. Among authors: lienard bm. Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24. Nature. 2007. PMID: 17589501

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

16 results

Search Page