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GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.
Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O'Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS; GROUP investigators; International Schizophrenia Consortium. Chen X, et al. Among authors: chen j. Mol Psychiatry. 2011 Nov;16(11):1117-29. doi: 10.1038/mp.2010.96. Epub 2010 Sep 14. Mol Psychiatry. 2011. PMID: 20838396 Free PMC article.
Common genetic variants on 1p13.2 associate with risk of autism.
Xia K, Guo H, Hu Z, Xun G, Zuo L, Peng Y, Wang K, He Y, Xiong Z, Sun L, Pan Q, Long Z, Zou X, Li X, Li W, Xu X, Lu L, Liu Y, Hu Y, Tian D, Long L, Ou J, Liu Y, Li X, Zhang L, Pan Y, Chen J, Peng H, Liu Q, Luo X, Su W, Wu L, Liang D, Dai H, Yan X, Feng Y, Tang B, Li J, Miedzybrodzka Z, Xia J, Zhang Z, Luo X, Zhang X, St Clair D, Zhao J, Zhang F. Xia K, et al. Among authors: chen j. Mol Psychiatry. 2014 Nov;19(11):1212-9. doi: 10.1038/mp.2013.146. Epub 2013 Nov 5. Mol Psychiatry. 2014. PMID: 24189344
Common variants on 17q25 and gene-gene interactions conferring risk of schizophrenia in Han Chinese population and regulating gene expressions in human brain.
Guan L, Wang Q, Wang L, Wu B, Chen Y, Liu F, Ye F, Zhang T, Li K, Yan B, Lu C, Su L, Jin G, Wang H, Tian H, Wang L, Chen Z, Wang Y, Chen J, Yuan Y, Cong W, Zheng J, Wang J, Xu X, Liu H, Xiao W, Han C, Zhang Y, Jia F, Qiao X; Genetic REsearch on schizophrenia neTwork-China and Netherland (GREAT-CN); Zhang D, Zhang M, Ma H. Guan L, et al. Among authors: chen z, chen j, chen y. Mol Psychiatry. 2016 Sep;21(9):1244-50. doi: 10.1038/mp.2015.204. Epub 2016 Jan 5. Mol Psychiatry. 2016. PMID: 26728569
Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.
Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Brüske I, Landi MT, Bickeböller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K. Hancock DB, et al. Among authors: chen j, chen x. Transl Psychiatry. 2015 Oct 6;5(10):e651. doi: 10.1038/tp.2015.149. Transl Psychiatry. 2015. PMID: 26440539 Free PMC article.
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