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Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.
Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, Chakraborty AK, Hope TJ, Ravetch JV, Wardemann H, Nussenzweig MC. Mouquet H, et al. Among authors: chakraborty ak. Nature. 2010 Sep 30;467(7315):591-5. doi: 10.1038/nature09385. Nature. 2010. PMID: 20882016 Free PMC article.
Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.
Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, Smith JY, Blackmore S, Sanisetty S, Perry JR, Beck M, Lewis MG, Rinaldi W, Chakraborty AK, Poignard P, Nussenzweig MC, Burton DR. Barouch DH, et al. Among authors: chakraborty ak. Nature. 2013 Nov 14;503(7475):224-8. doi: 10.1038/nature12744. Epub 2013 Oct 30. Nature. 2013. PMID: 24172905 Free PMC article.
Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo.
Lu CL, Murakowski DK, Bournazos S, Schoofs T, Sarkar D, Halper-Stromberg A, Horwitz JA, Nogueira L, Golijanin J, Gazumyan A, Ravetch JV, Caskey M, Chakraborty AK, Nussenzweig MC. Lu CL, et al. Among authors: chakraborty ak. Science. 2016 May 20;352(6288):1001-4. doi: 10.1126/science.aaf1279. Epub 2016 May 5. Science. 2016. PMID: 27199430 Free PMC article.
Evolving concepts of specificity in immune reactions.
Eisen HN, Chakraborty AK. Eisen HN, et al. Among authors: chakraborty ak. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22373-80. doi: 10.1073/pnas.1012051108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2010. PMID: 21173256 Free PMC article.
391 results