Breckenridge AM - Search Results

1

Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults.

Watkins WM, Mberu EK, Nevill CG, Ward SA, Breckenridge AM, Koech DK. Watkins WM, et al. Among authors: breckenridge am. Trans R Soc Trop Med Hyg. 1990 Jul-Aug;84(4):492-5. doi: 10.1016/0035-9203(90)90010-c. Trans R Soc Trop Med Hyg. 1990. PMID: 2091335

2

Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.

Ward SA, Watkins WM, Mberu E, Saunders JE, Koech DK, Gilles HM, Howells RE, Breckenridge AM. Ward SA, et al. Among authors: breckenridge am. Br J Clin Pharmacol. 1989 Jun;27(6):781-7. doi: 10.1111/j.1365-2125.1989.tb03440.x. Br J Clin Pharmacol. 1989. PMID: 2757894 Free PMC article.

3

The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.

Helsby NA, Ward SA, Edwards G, Howells RE, Breckenridge AM. Helsby NA, et al. Among authors: breckenridge am. Br J Clin Pharmacol. 1990 Oct;30(4):593-8. doi: 10.1111/j.1365-2125.1990.tb03818.x. Br J Clin Pharmacol. 1990. PMID: 2291871 Free PMC article.

4

The multiple dose pharmacokinetics of proguanil.

Helsby NA, Edwards G, Breckenridge AM, Ward SA. Helsby NA, et al. Among authors: breckenridge am. Br J Clin Pharmacol. 1993 Jun;35(6):653-6. doi: 10.1111/j.1365-2125.1993.tb04197.x. Br J Clin Pharmacol. 1993. PMID: 8329294 Free PMC article.

5

The activation of the biguanide antimalarial proguanil co-segregates with the mephenytoin oxidation polymorphism--a panel study.

Ward SA, Helsby NA, Skjelbo E, Brøsen K, Gram LF, Breckenridge AM. Ward SA, et al. Among authors: breckenridge am. Br J Clin Pharmacol. 1991 Jun;31(6):689-92. doi: 10.1111/j.1365-2125.1991.tb05594.x. Br J Clin Pharmacol. 1991. PMID: 1867963 Free PMC article.

6

In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs.

Winstanley PA, Mberu EK, Szwandt IS, Breckenridge AM, Watkins WM. Winstanley PA, et al. Among authors: breckenridge am. Antimicrob Agents Chemother. 1995 Apr;39(4):948-52. doi: 10.1128/AAC.39.4.948. Antimicrob Agents Chemother. 1995. PMID: 7786001 Free PMC article.

7

The effect of malaria infection on the disposition of quinine and quinidine in the rat isolated perfused liver preparation.

Mansor SM, Ward SA, Edwards G, Hoaksey PE, Breckenridge AM. Mansor SM, et al. Among authors: breckenridge am. J Pharm Pharmacol. 1990 Jun;42(6):428-32. doi: 10.1111/j.2042-7158.1990.tb06584.x. J Pharm Pharmacol. 1990. PMID: 1979624

8

Drug metabolism and tropical disease.

Breckenridge A, Awadzi K, Back DJ, Edwards G, Gilles H, Orme M, Ward S. Breckenridge A, et al. Biochem Soc Trans. 1984 Feb;12(1):90-5. doi: 10.1042/bst0120090. Biochem Soc Trans. 1984. PMID: 6705997 No abstract available.

9

In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.

Helsby NA, Ward SA, Howells RE, Breckenridge AM. Helsby NA, et al. Among authors: breckenridge am. Br J Clin Pharmacol. 1990 Aug;30(2):287-91. doi: 10.1111/j.1365-2125.1990.tb03777.x. Br J Clin Pharmacol. 1990. PMID: 2206791 Free PMC article.

10

The binding of the antimalarial arteether to human plasma proteins in-vitro.

Wanwimolruk S, Edwards G, Ward SA, Breckenridge AM. Wanwimolruk S, et al. Among authors: breckenridge am. J Pharm Pharmacol. 1992 Nov;44(11):940-2. doi: 10.1111/j.2042-7158.1992.tb03243.x. J Pharm Pharmacol. 1992. PMID: 1361544

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