Klijn C - Search Results

1

Somatic structural rearrangements in genetically engineered mouse mammary tumors.

Varela I, Klijn C, Stephens PJ, Mudie LJ, Stebbings L, Galappaththige D, van der Gulden H, Schut E, Klarenbeek S, Campbell PJ, Wessels LF, Stratton MR, Jonkers J, Futreal PA, Adams DJ. Varela I, et al. Among authors: klijn c. Genome Biol. 2010;11(10):R100. doi: 10.1186/gb-2010-11-10-r100. Epub 2010 Oct 13. Genome Biol. 2010. PMID: 20942901 Free PMC article.

2

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma.

Kas SM, de Ruiter JR, Schipper K, Annunziato S, Schut E, Klarenbeek S, Drenth AP, van der Burg E, Klijn C, Ten Hoeve JJ, Adams DJ, Koudijs MJ, Wesseling J, Nethe M, Wessels LFA, Jonkers J. Kas SM, et al. Among authors: klijn c. Nat Genet. 2017 Aug;49(8):1219-1230. doi: 10.1038/ng.3905. Epub 2017 Jun 26. Nat Genet. 2017. PMID: 28650484

3

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.

Holstege H, van Beers E, Velds A, Liu X, Joosse SA, Klarenbeek S, Schut E, Kerkhoven R, Klijn CN, Wessels LF, Nederlof PM, Jonkers J. Holstege H, et al. BMC Cancer. 2010 Aug 24;10:455. doi: 10.1186/1471-2407-10-455. BMC Cancer. 2010. PMID: 20735817 Free PMC article.

4

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

Drost R, Bouwman P, Rottenberg S, Boon U, Schut E, Klarenbeek S, Klijn C, van der Heijden I, van der Gulden H, Wientjens E, Pieterse M, Catteau A, Green P, Solomon E, Morris JR, Jonkers J. Drost R, et al. Among authors: klijn c. Cancer Cell. 2011 Dec 13;20(6):797-809. doi: 10.1016/j.ccr.2011.11.014. Cancer Cell. 2011. PMID: 22172724 Free article.

5

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

Klijn C, Koudijs MJ, Kool J, ten Hoeve J, Boer M, de Moes J, Akhtar W, van Miltenburg M, Vendel-Zwaagstra A, Reinders MJ, Adams DJ, van Lohuizen M, Hilkens J, Wessels LF, Jonkers J. Klijn C, et al. PLoS One. 2013 May 14;8(5):e62113. doi: 10.1371/journal.pone.0062113. Print 2013. PLoS One. 2013. PMID: 23690930 Free PMC article.

6

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

Bouwman P, Drost R, Klijn C, Pieterse M, van der Gulden H, Song JY, Szuhai K, Jonkers J. Bouwman P, et al. Among authors: klijn c. J Pathol. 2011 May;224(1):10-21. doi: 10.1002/path.2861. Epub 2011 Mar 14. J Pathol. 2011. PMID: 21404276

7

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

Koudijs MJ, Klijn C, van der Weyden L, Kool J, ten Hoeve J, Sie D, Prasetyanti PR, Schut E, Kas S, Whipp T, Cuppen E, Wessels L, Adams DJ, Jonkers J. Koudijs MJ, et al. Among authors: klijn c. Genome Res. 2011 Dec;21(12):2181-9. doi: 10.1101/gr.112763.110. Epub 2011 Aug 18. Genome Res. 2011. PMID: 21852388 Free PMC article.

8

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.

Drost R, Dhillon KK, van der Gulden H, van der Heijden I, Brandsma I, Cruz C, Chondronasiou D, Castroviejo-Bermejo M, Boon U, Schut E, van der Burg E, Wientjens E, Pieterse M, Klijn C, Klarenbeek S, Loayza-Puch F, Elkon R, van Deemter L, Rottenberg S, van de Ven M, Dekkers DH, Demmers JA, van Gent DC, Agami R, Balmaña J, Serra V, Taniguchi T, Bouwman P, Jonkers J. Drost R, et al. Among authors: klijn c. J Clin Invest. 2016 Aug 1;126(8):2903-18. doi: 10.1172/JCI70196. Epub 2016 Jul 25. J Clin Invest. 2016. PMID: 27454287 Free PMC article.

9

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

Klijn C, Bot J, Adams DJ, Reinders M, Wessels L, Jonkers J. Klijn C, et al. PLoS Comput Biol. 2010 Jan;6(1):e1000631. doi: 10.1371/journal.pcbi.1000631. Epub 2010 Jan 1. PLoS Comput Biol. 2010. PMID: 20052266 Free PMC article.

10

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.

Klijn C, Holstege H, de Ridder J, Liu X, Reinders M, Jonkers J, Wessels L. Klijn C, et al. Nucleic Acids Res. 2008 Feb;36(2):e13. doi: 10.1093/nar/gkm1143. Epub 2008 Jan 10. Nucleic Acids Res. 2008. PMID: 18187509 Free PMC article.

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