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Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B. Mrkonjic M, et al. Among authors: daftary d. PLoS One. 2010 Oct 13;5(10):e13314. doi: 10.1371/journal.pone.0013314. PLoS One. 2010. PMID: 20967208 Free PMC article.
MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer.
Mrkonjic M, Raptis S, Green RC, Monga N, Daftary D, Dicks E, Younghusband HB, Parfrey PS, Gallinger SS, McLaughlin JR, Knight JA, Bapat B. Mrkonjic M, et al. Among authors: daftary d. Carcinogenesis. 2007 Dec;28(12):2575-80. doi: 10.1093/carcin/bgm229. Epub 2007 Oct 17. Carcinogenesis. 2007. PMID: 17942459
Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients.
Rawson JB, Manno M, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Rawson JB, et al. Among authors: daftary d. Carcinogenesis. 2011 May;32(5):741-7. doi: 10.1093/carcin/bgr020. Epub 2011 Feb 8. Carcinogenesis. 2011. PMID: 21304055 Free PMC article.
Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients.
Rawson JB, Mrkonjic M, Daftary D, Dicks E, Buchanan DD, Younghusband HB, Parfrey PS, Young JP, Pollett A, Green RC, Gallinger S, McLaughlin JR, Knight JA, Bapat B. Rawson JB, et al. Among authors: daftary d. Br J Cancer. 2011 Jun 7;104(12):1906-12. doi: 10.1038/bjc.2011.165. Epub 2011 May 17. Br J Cancer. 2011. PMID: 21587258 Free PMC article.
Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history.
Weisenberger DJ, Levine AJ, Long TI, Buchanan DD, Walters R, Clendenning M, Rosty C, Joshi AD, Stern MC, LeMarchand L, Lindor NM, Daftary D, Gallinger S, Selander T, Bapat B, Newcomb PA, Campbell PT, Casey G, Ahnen DJ, Baron JA, Haile RW, Hopper JL, Young JP, Laird PW, Siegmund KD; Colon Cancer Family Registry. Weisenberger DJ, et al. Among authors: daftary d. Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):512-519. doi: 10.1158/1055-9965.EPI-14-1161. Epub 2015 Jan 13. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 25587051 Free PMC article.
75 results