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Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer.
Mrkonjic M, Roslin NM, Greenwood CM, Raptis S, Pollett A, Laird PW, Pethe VV, Chiang T, Daftary D, Dicks E, Thibodeau SN, Gallinger S, Parfrey PS, Younghusband HB, Potter JD, Hudson TJ, McLaughlin JR, Green RC, Zanke BW, Newcomb PA, Paterson AD, Bapat B. Mrkonjic M, et al. Among authors: newcomb pa. PLoS One. 2010 Oct 13;5(10):e13314. doi: 10.1371/journal.pone.0013314. PLoS One. 2010. PMID: 20967208 Free PMC article.
Evidence for an association between JC virus and colorectal neoplasia.
Boland CR, Bigler J, Newcomb PA, Lampe JW, Potter JD. Boland CR, et al. Among authors: newcomb pa. Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2285-6; author reply 2286. Cancer Epidemiol Biomarkers Prev. 2004. PMID: 15598796 No abstract available.
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X.
Lindor NM, Rabe K, Petersen GM, Haile R, Casey G, Baron J, Gallinger S, Bapat B, Aronson M, Hopper J, Jass J, LeMarchand L, Grove J, Potter J, Newcomb P, Terdiman JP, Conrad P, Moslein G, Goldberg R, Ziogas A, Anton-Culver H, de Andrade M, Siegmund K, Thibodeau SN, Boardman LA, Seminara D. Lindor NM, et al. JAMA. 2005 Apr 27;293(16):1979-85. doi: 10.1001/jama.293.16.1979. JAMA. 2005. PMID: 15855431 Free PMC article.
Insulin-like growth factor polymorphisms and colorectal cancer risk.
Morimoto LM, Newcomb PA, White E, Bigler J, Potter JD. Morimoto LM, et al. Among authors: newcomb pa. Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1204-11. doi: 10.1158/1055-9965.EPI-04-0695. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15894673
595 results